51440-81-4

Basic information

• Product Name: Z-3-AMINOBUTYRIC ACID
• Synonyms: RARECHEM AK RZ 0058;Z-3-AMINOBUTYRIC ACID;Z-DL-BETA-HOMOALANINE;Z-DL-BETA-HOMOALA-OH;Z-3-Aminobutyric acid, Z-DL-β-Homoala-OH;Z-DL-β-Homoalanine;3-{[(Benzyloxy)carbonyl]amino}butanoic acid;Z-DL-β-Homoala-OH
• CAS NO: 51440-81-4
• Molecular Formula: C₁₂H₁₅NO₄
• Molecular Weight: 237.25
• Mol File: 51440-81-4.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Z-3-AMINOBUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: Z-3-AMINOBUTYRIC ACID(51440-81-4)
• EPA Substance Registry System: Z-3-AMINOBUTYRIC ACID(51440-81-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 51440-81-4(Hazardous Substances Data)

Usage

General Description

Z-3-aminobutyric acid, also known as β-3-aminobutyric acid, is a chemical compound with the molecular formula C4H9NO2. It is an organic compound classified as an amino acid derivative. This chemical is a derivative of the neurotransmitter γ-aminobutyric acid (GABA), and it plays a role in the metabolism and biosynthesis of GABA in the brain and central nervous system. It is also believed to have potential therapeutic applications in the treatment of anxiety, depression, and other neurological disorders. Z-3-aminobutyric acid is also used as a building block in the synthesis of pharmaceuticals and biologically active compounds. Overall, Z-3-aminobutyric acid is an important chemical with various potential applications in medicine and industry.

Upstream product

• 501-53-1 benzyl chloroformate 
• 2835-82-7 3-aminobutyric acid 

Downstream Products

• 2835-82-7 3-aminobutyric acid 
• 121054-27-1 Methyl (+/-)-3-<(benzyloxycarbonyl)amino>butanoate 
• 137945-99-4 N¹,N⁴-bis<3-<(carbobenzyloxy)amino>butyryl>-1,4-diaminobutane 
• 866395-21-3 (-)-(3R)-3-((benzyloxycarbonyl)amino)butanol 
• 168827-91-6 (3-hydroxy-1-(S)-methyl-propyl)carbamic acid benzyl ester 
• 1609650-85-2 Cbz-D,L-β-Homo-Ala-Bt 
• 1609650-90-9 Cbz-D,L-β-Homo-Ala-D-Pro-OH 
• 1592690-37-3 C₂₅H₄₄N₂O₅Si 
• 1592688-90-8 C₁₉H₃₀N₂O₅ 
• 1446746-94-6 3-(N-benzyloxycarbonyl)amino-1-butyl azide 

Relevant articles and documents

The kinetic resolution of oxazinones by alcoholysis: access to orthogonally protected β-amino acids

The catalytic, alcoholytic kinetic resolution of oxazinones is reported. A novel, stereochemically dense cinchona alkaloid-based catalyst can facilitate the highly enantiodiscriminatory (Sup to 101) ring-opening of oxazinones equipped with electrophilic aryl units to generate orthogonally protected β-amino acids for the first time.

ARYL SULTAM DERIVATIVES AS RORc MODULATORS

Compounds of the formula I: or a pharmaceutical salt thereof, wherein p, s, A, R3 and Re are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.

HETEROARYL AMIDE SULTAM DERIVATIVES AS RORc MODULATORS

Compounds of the formula I: (I) or a pharmaceutical salt thereof, wherein m, n, p, q, Het, A, W, R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.