51599-74-7

Basic information

• Product Name: 1-acetylazetidin-2-one
• Synonyms: 1-acetylazetidin-2-one
• CAS NO: 51599-74-7
• Molecular Weight: 113.116
• Mol File: 51599-74-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-acetylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetylazetidin-2-one(51599-74-7)
• EPA Substance Registry System: 1-acetylazetidin-2-one(51599-74-7)

Safety Data

• Hazardous Substances Data: 51599-74-7(Hazardous Substances Data)

Upstream product

• 110967-04-9 1-isopropylazetidin-2-one 

Downstream Products

• 246181-66-8 1-acetyl-4-fluoro-2-azetidinone 

Relevant articles and documents

Ruthenium Tetroxide Oxidation of N-Alkyllactams

Ruthenium tetroxide (RuO4) oxidation of N-alkyllactams proceeded regioselectively depending on the size of lactam ring, except for the seven-membered ring.Four- and eight-membered N-methyl- and N-ethyllactams were oxidized at the exocyclic α-carbon adjacent to nitrogen to produce the N-acyllactams and NH-lactams, while five- and six-membered lactams underwent endocyclic oxidation to yield the cyclic imides.Oxidation of seven-membered lactams yielded a mixture of products arising from both exocyclic and endocyclic oxidations.These regioselectivities were confirmed in the oxidation of substrates having a tertiary carbon at the oxidation position.Keywords---oxidation; ruthenium tetroxide oxidation; regioselective oxidation; hydroxylation; imide synthesis; N-alkyllactam; N-acyllactams; imide; ruthenium tetroxide; two-phase method