51866-19-4 Usage
Description
6-Ethylguanine is an alkylated mutagen derived from guanine, one of the five nucleobases found in biological nucleic acids. Its detection is often indicative of carcinoma, making it a significant biomarker for cancer research and diagnosis.
Uses
Used in Cancer Research and Diagnosis:
6-Ethylguanine is used as a biomarker for the detection of carcinoma. Its presence in biological samples can indicate the presence of cancer, particularly carcinoma, aiding in early diagnosis and treatment planning.
Used in Pharmaceutical Development:
6-Ethylguanine, being an alkylated mutagen, can be utilized in the development of targeted cancer therapies. Understanding its interaction with nucleic acids and its mutagenic properties can lead to the creation of novel drugs that specifically target cancer cells, potentially improving treatment outcomes and reducing side effects.
Used in Drug Delivery Systems:
Similar to gallotannin, 6-ethylguanine can be incorporated into drug delivery systems to enhance its bioavailability and therapeutic efficacy. By employing various organic and metallic nanoparticles as carriers, the delivery, targeting, and overall effectiveness of 6-ethylguanine in cancer treatment can be improved.
Check Digit Verification of cas no
The CAS Registry Mumber 51866-19-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,8,6 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51866-19:
(7*5)+(6*1)+(5*8)+(4*6)+(3*6)+(2*1)+(1*9)=134
134 % 10 = 4
So 51866-19-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N5O/c1-2-13-6-4-5(10-3-9-4)11-7(8)12-6/h3-4H,2H2,1H3,(H2,8,9,10,11)
51866-19-4Relevant articles and documents
Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides
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, (2008/06/13)
A method for treating two specific protozoal infections, Trichomonas vaginalis and Giardia lamblia, comprising the administration to a mammal in need thereof one of the following purine nucleosides: 2,6-diamino-9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-9H-purine 2-amino-9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-9H-purine 2-amino-9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-6-methoxy-9H-purine.
