52289-54-0Relevant articles and documents
Regiospecific Oxidation of Methyl Groups in Dimethylanisoles
Hauser, Frank M.,Ellenberger, Suzanne R.
, p. 723 - 724 (1987)
Dimethylanisoles in which one of the methyl groups is meta and the other is ortho or para are regiospecifically oxidized in high yield to the corresponding ortho- and para-substituted aldehydes by copper(II) and peroxydisulfate.Subsequent oxidation of the
Chemoselective oxidation and deprotection of para-methoxybenzylic position with (diacetoxyiodo)benzene in acetic-trifluoroacetic acid
Lin, Chun-Yu,Yang, Ping-Shin,Chou, Pang-Yu,Ong, Chi Wi
, p. 365 - 367 (2018/01/01)
(Diacetoxyiodo)benzene in the presence of acetic–trifluoroacetic acid in THF has been developed for the chemoselective para-methoxybenzylic C–H bond oxidation to provide aryl carbonyl compounds at room temperature. The reaction condition is also applicable for the chemoselective deprotection of para-methoxybenzyl (PMB) ether in the presence of benzyl ether.
A 4-methoxy-2-methyl-benzyl cyanide synthesis method
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Paragraph 0034; 0035, (2019/02/02)
The invention relates to a synthesis method for 4-methoxy-2-methyl benzyl cyanide. The synthesis method takes 3, 4-dimethylphenol which is cheap and simple and easy to purchase as the raw material, and comprises six steps: methylation, oxidation, Witting reaction, alkene ether hydrolysis, oximation and dehydration. The synthesis method uses the simple and cheap raw material, is simple to operate, is easy for industrial production, has short production cycle, only needs purification in the last step of the six so as to obtain high-quality 4-methoxy-2-methyl benzyl cyanide, and avoids using extremely toxic substances like NaCN and KCN, thus filling the blank home and abroad.