52596-90-4

Basic information

• Product Name: Pyridine, 4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]-
• CAS NO: 52596-90-4
• Molecular Formula: C14H11N3O
• Molecular Weight: 237.261
• Mol File: 52596-90-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Pyridine, 4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]-(52596-90-4)
• EPA Substance Registry System: Pyridine, 4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]-(52596-90-4)

Safety Data

• Hazardous Substances Data: 52596-90-4(Hazardous Substances Data)

Upstream product

• 54-85-3 isoniazid 
• 104-87-0 4-methyl-benzaldehyde 
• 325472-26-2 4-methylbenzoic acid (pyridine-4-carbonyl)hydrazide 
• 43002-64-8 ethyl 4-methylbenzimidate hydrochloride 
• 209797-67-1 ethyl p-methylbenzoateformylhydrazone 
• 14389-12-9 5-(4-pyridyl)tetrazole 
• 874-60-2 4-methyl-benzoyl chloride 
• 119072-55-8 tert-butylisonitrile 
• 624-31-7 4-tolyl iodide 

Downstream Products

• 52822-28-3 4-{5-[4-(trans-2-dibenzofuran-3-yl-vinyl)-phenyl]-[1,3,4]oxadiazol-2-yl}-pyridine 
• 52596-64-2 2-{4-[4-(5-pyridin-4-yl-[1,3,4]oxadiazol-2-yl)-trans-styryl]-phenyl}-2H-naphtho[1,2-d][1,2,3]triazole 
• 943860-99-9 2-phenyl-7-(5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 943861-00-5 2-(4-methylphenyl)-7-(5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 943861-01-6 2-(4-methoxyphenyl)-7-(5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 

Relevant articles and documents

Three AgI, CuI and CdII coordination polymers based on the new asymmetrical ligand 2-{4-[(1H-imidazol-1-yl)methyl]phenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazole: syntheses, characterization and emission properties

The new asymmetrical organic ligand 2-{4-[(1H-imidazol-1-yl)methyl]phenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazole (L, C17H13N5O), containing pyridine and imidazole terminal groups, as well as potential oxdiazole coordination si

Use of ester formylhydrazones for the synthesis of 1,2,4-triazole and 1,3,4-oxadiazole derivatives

A series of ester formylhydrazones were synthesised by the reaction of alkyl imidate hydrochlorides with ormylhydrazine. Treatment of the ester formylhydrazones with acetic acid hydrazide, isonicotinic acid hydrazide, nicotinicacid hydrazide, and 4-hydroxybenzhydrazide resulted in the formation of either 4-acylamino-4H-1,2,4-triazoles or 2,5-disubstituted 1,3,4-oxadiazoles. 3-Alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesised by the reaction of the ester formylhydrazones with carbohydrazide. Some arylidenamino compounds were synthesized by the reaction of 4-amino-4,5-dihydro-1H-1,2,4- triazol-5-ones with several aldehydes. These compounds were characterised by elemental analyses, IR, 1H NMR, and UV spectral techniques.

Synthesis and biological screening of Some 1,3,4-oxadiazoles

Treatment of Schiff bases with yellow mercuric oxide and iodine in DMF medium yields the title compounds 1,3,4-oxadiazoles (4a-j). The structures of the newly synthesized compounds were assigned on the basis of IR, 1H NMR, Mass spectral data and elemental analysis. All the new compounds were evaluated for their in vitro antibacterial and antifungal activity. Some of the new compounds showed good activity against some bacteria when compared with the standard drug.