53054-03-8

Basic information

• Product Name: tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate
• Synonyms: tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate
• CAS NO: 53054-03-8
• Molecular Weight: 288.387
• Mol File: 53054-03-8.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate(53054-03-8)
• EPA Substance Registry System: tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate(53054-03-8)

Safety Data

• Hazardous Substances Data: 53054-03-8(Hazardous Substances Data)

Usage

General Description

Tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate is a chemical compound with the molecular formula C13H27N3O4. It is a derivative of the amino acid valine, with a tert-butyl group attached to the alpha carbon and a tert-butyl ester group attached to the amino group. tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate is often used as a building block in organic synthesis and pharmaceutical research, due to its stable and versatile reactivity. It can be used in the preparation of various peptides and protein derivatives, as well as in the development of potential drug candidates. Additionally, it may have applications in the field of medicinal chemistry and drug discovery.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 3184-13-2 L-ornithine hydrochloride 
• 53054-01-6 (S)-2-amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid tert-butyl ester 
• 3304-51-6 N-carboxybenzyl-L-ornithine 
• 2480-93-5 Boc-Orn(Z)-OH 
• 21887-64-9 N₂-(tert-butoxycarbonyl)-L-ornithine 
• 75-65-0 tert-butyl alcohol 
• 53054-02-7 N_α-(1,1-dimethylethoxycarbonyl)-N_δ-(phenylmethoxycarbonyl)-L-ornithine 1,1-dimethylethyl ester 

Downstream Products

• 1386433-38-0 C₆₂H₈₅N₉O₁₄S 
• 1234623-57-4 N^ω-benzyloxycarbonyl-N^α-tert-butyloxycarbonyl-N^ω'-(methoxycarbonyl)methoxy-L-arginine t-butyl ester 
• 1061261-93-5 N^ω-benzyloxycarbonyl-N^α-tert-butyloxycarbonyl-N^ω'-methoxy-L-arginine t-butyl ester 
• 1061261-89-9 N^ω-benzyloxycarbonyl-N^α-tert-butyloxycarbonyl-L-thiocitrulline tert-butyl ester 
• 53054-07-2 L-NOHA 
• 133565-52-3 α-N-t-butoxycarbonyl-N^G-benzyloxy-N^6'-t-butoxycarbonyl-L-arginine-t-butyl ester 
• 133565-49-8 α-N-t-butoxycarbonyl-δ-(thioureido)-L-norvaline-t-butyl ester 
• 133565-48-7 N^ω-Hydroxy-L-arginine dihydrochloride 
• 13215-18-4 N^δ-acetyl-L-ornithine 
• 227007-19-4 α-N-tert-butoxycarbonyl-ω-N-hydroxy(O-benzyl)-L-citrulline tert-butyl ester 
• 225530-19-8 (2S)-tert-butyl 2-N-(tert-butoxycarbonyl)amino-5-N'-(2-(3-N-triphenylmethyl)amino-pyridinyl)ureidopentanoate 
• 225530-20-1 (2S)-tert-butyl 2-N-(tert-butoxycarbonyl)amino-5-N-(2-(1-triphenylmethyl)-1H-imidazo-[4,5-b]-pyridinyl)aminopentanoate 

Relevant articles and documents

Short self-assembling peptides with a urea bond: A new type of supramolecular peptide hydrogel materials

There is an increasing need to develop short self-assembling peptides (SAPs) that can form hydrogels for cell engineering and biomedical applications. In this study, we proposed new short self-assembling peptides with a symmetric structure via a urea bond

Synthesis and precursor-directed biosynthesis of new hormaomycin analogues

Several new analogues of hormaomycin (1), a peptide lactone with interesting biological activities, were prepared by total synthesis or by precursor-directed biosynthesis. The new analogues 2a-c, 3a-c, O-MOM-1 and epi-O-MOM-1 as well as the model acyl tri

An expeditious synthesis of pentosidine, an advanced glycation end product

The chemical synthesis of pentosidine (1), an advanced glycation end product, was achieved via the asymmetric alkylation of the chiral schiff base derived from (+)-2-hydroxy-3-pinanone ((+)-HyPN) and glycine tert-butyl ester, the mercury salt mediated intramolecular guanylation, and the regioselective alkylation of imidazo[4,5-b]pyridine ring. This reliable synthetic achievement will promise availability of pentosidine (1) in quantities.