53151-13-6

Basic information

• Product Name: [2-Chloro-2-methyl-prop-(E)-ylidene]-phenyl-amine
• Synonyms: [2-Chloro-2-methyl-prop-(E)-ylidene]-phenyl-amine
• CAS NO: 53151-13-6
• Molecular Weight: 181.665
• Mol File: 53151-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-Chloro-2-methyl-prop-(E)-ylidene]-phenyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [2-Chloro-2-methyl-prop-(E)-ylidene]-phenyl-amine(53151-13-6)
• EPA Substance Registry System: [2-Chloro-2-methyl-prop-(E)-ylidene]-phenyl-amine(53151-13-6)

Safety Data

• Hazardous Substances Data: 53151-13-6(Hazardous Substances Data)

Upstream product

• 917-93-1 2-chloroisobutyraldehyde 
• 62-53-3 aniline 

Downstream Products

• 70987-75-6 N-(2-Methyl-propenyl)-N-phenyl-acetamide 
• 264907-63-3 3-methyl-2-phenylamino-2-butenenitrile 
• 2760-38-5 2-hydroxy-2-methylpropionanilide 
• 264907-73-5 3-hydroperoxy-3-methyl-2-phenyliminobutyronitrile 

Relevant articles and documents

Reactions of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile with copper(II) acetate: Synthesis of 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles

Treatment of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile 15, prepared by reactions of N-aryl α-cyanoenamines 3 with Cu(OAc)2·H2O (2 equiv.) in the presence of pyridine (2 equiv.) in EtOH at reflux, and with Cu(OAc)2·H2O (1 equiv.) in HOAc at reflux gave 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles 11 in moderate to good yields.