5335-69-3Relevant articles and documents
C2-Selective silylation of pyridines by a rhodium-aluminum complex
Hara, Naofumi,Uemura, Nao,Nakao, Yoshiaki
, p. 5957 - 5960 (2021/06/18)
We have developed a C2-selective mono-silylation of a variety of pyridines using a Rh-Al complex. Both the site- and mono-selectivity are controlledviathe pyridine coordination to the Lewis-acidic Al center prior to the activation of the pyridine C(2)-H bond at the proximal Rh center. A reaction mechanism is proposed based on several mechanistic studies, including the isolation of a (2-pyridyl)silylrhodium intermediate.
A microwave-assisted highly practical chemoselective esterification and amidation of carboxylic acids
Pathak, Gunindra,Das, Diparjun,Rokhum, Lalthazuala
, p. 93729 - 93740 (2016/10/21)
The ubiquitousness of esters and amide functionalities makes their coupling reaction one of the most sought-after organic transformations. Herein, we have described an efficient microwave-assisted synthesis of esters and amides. Soluble triphenylphosphine, in conjugation with molecular iodine, gave the desired products without the requirement for a base/catalyst. In addition, a solid-phase synthetic route is incorporated for the said conversion, which has added advantages over solution-phase pathways, such as low moisture sensitivity, easy handling, isolation of the product by simple filtration, and reusability. In short, our method is simple, mild, green, and highly chemoselective in nature.
Esterification of free fatty acids (Biodiesel) using nano sulfated-titania as catalyst in solvent-free conditions
Hosseini-Sarvari, Mona,Sodagar, Esmat
, p. 229 - 238 (2013/05/09)
Nano sulfated titania was tested as catalyst for esterification of free fatty acids, specially methanolic and ethanolic esterification of stearic acid (biodiesels). Factorial design evidenced a positive effect of reaction temperature, amount of catalyst, and solvents on ester conversion. This nano-sized sulfated titania has been prepared by a sol-gel hydrothermal process. This prepared sulfated titania showed high catalytic activity in direct esterification of fatty acids as well as benzoic acids with various alcohols and phenols under solvent-free conditions. This method is of great value because of its environmentally benign character, easy handling, high yields, convenient operation, and green. FT-IR studies are shown that the catalyst can be reused for acylation without loss of catalytic activity.