5347-68-2 Usage
Description
2,3-Dimethylpiperidine is an organic compound with the molecular formula C7H15N. It is a heterocyclic compound featuring a six-membered piperidine ring with two methyl groups attached at the 2nd and 3rd positions. 2,3-DIMETHYLPIPERIDINE is known for its versatile chemical properties and is commonly utilized as a building block in the synthesis of various organic molecules.
Uses
Used in Pharmaceutical Industry:
2,3-Dimethylpiperidine is used as a synthetic intermediate for the development of novel pharmaceutical compounds. Its unique structure allows it to be a key component in the synthesis of various drug candidates, particularly those with potential applications in the treatment of different medical conditions.
Used in Chemical Synthesis:
2,3-Dimethylpiperidine serves as a valuable building block in the synthesis of a wide range of organic compounds, including those with potential applications in various industries such as agriculture, materials science, and specialty chemicals. Its reactivity and structural diversity make it a popular choice for researchers and chemists working on the development of new molecules with specific properties and functions.
Specific Application:
2,3-Dimethylpiperidine is involved in the synthesis of novel 3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid amide compounds. These compounds may have potential applications in various fields, such as pharmaceuticals, agrochemicals, or materials science, depending on their specific properties and characteristics. The use of 2,3-dimethylpiperidine in this synthesis highlights its importance as a versatile and valuable chemical intermediate.
Check Digit Verification of cas no
The CAS Registry Mumber 5347-68-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,4 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5347-68:
(6*5)+(5*3)+(4*4)+(3*7)+(2*6)+(1*8)=102
102 % 10 = 2
So 5347-68-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H15N/c1-6-4-3-5-8-7(6)2/h6-8H,3-5H2,1-2H3
5347-68-2Relevant articles and documents
Borane-Catalyzed Reduction of Pyridines via a Hydroboration/Hydrogenation Cascade
Yang, Zhao-Ying,Luo, Heng,Zhang, Ming,Wang, Xiao-Chen
, p. 10824 - 10829 (2021/09/08)
We have developed a method for a B(C6F5)3-catalyzed hydroboration/hydrogenation cascade reduction of pyridines. The method was particularly effective for 2,3-disubstituted pyridines, which generated piperidines in high yields with high cis selectivity. Mechanistic studies indicated that the pyridine substrates and the piperidine products sequentially acted as bases in cooperation with B(C6F5)3to split H2. The broad functional group tolerance of the method allowed its use for the synthesis of some biologically active molecules.
Novel 3-phenylprop-2-ynylamines as inhibitors of mammalian squalene epoxidase.
Musso, David L,Clarke, Morris J,Kelley, James L,Boswell, G Evan,Chen, Grace
, p. 498 - 506 (2007/10/03)
The synthesis of a novel series of 3-phenylprop-2-ynylamines as selective mammalian squalene epoxidase inhibitors is described. Structure activity relationship studies led to the discovery of compound 19, 1-[3-(3,5-dichlorophenyl)-prop-2-ynyl]-3- methylpiperidine hydrochloride with an IC50 of 2.8 +/- 0.6 microM against rat liver squalene epoxidase. Against 23 strains of fungal squalene epoxidase compound 19 was found to be inactive.