5347-99-9

Basic information

• Product Name: 2,5-dichloro-N-(3,5-dimethylphenyl)benzenesulfonamide
• Synonyms: benzenesulfonamide, 2,5-dichloro-N-(3,5-dimethylphenyl)-
• CAS NO: 5347-99-9
• Molecular Formula: C₈H₈N₆O₄
• Molecular Weight: 330.2295
• Mol File: 5347-99-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 460.1°C at 760 mmHg
• Flash Point: 232°C
• Density: 1.405g/cm³
• Vapor Pressure: 1.2E-08mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: 2,5-dichloro-N-(3,5-dimethylphenyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dichloro-N-(3,5-dimethylphenyl)benzenesulfonamide(5347-99-9)
• EPA Substance Registry System: 2,5-dichloro-N-(3,5-dimethylphenyl)benzenesulfonamide(5347-99-9)

Safety Data

• Hazardous Substances Data: 5347-99-9(Hazardous Substances Data)

Usage

Classification

Sulfonamide

Chemical structure

Benzene ring with 2 chlorine atoms at 2 and 5 positions, sulfonamide group attached to a 3,5-dimethylphenyl group

Uses

commonly used in the synthesis of pharmaceuticals and agrochemicals; antimicrobial and herbicidal properties; carbonic anhydrase inhibitor; potential therapeutic agent for certain medical conditions

Uses

Synthesis of pharmaceuticals and agrochemicals
Antimicrobial and herbicidal properties
Carbonic anhydrase inhibitor
Potential therapeutic agent for certain medical conditions

Precautions

Handle with caution due to potential health hazards and toxicity.

-Properties

Antimicrobial, herbicidal, carbonic anhydrase inhibitor, therapeutic potential, toxic.

Chemical Class

Sulfonamides

Structure

Benzene ring with chlorine atoms at 2 and 5 positions
Sulfonamide group attached to a 3,5-dimethylphenyl group

Caution

Handle with caution due to potential health hazards and toxicity

Upstream product

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Relevant articles and documents

Synthesis and insecticidal activity of novel 1,2,4-triazole derivatives containing trifluoroacetyl moieties

A series of compounds containing trifluoroacetyl groups were synthesized, and their insecticidal activity against Nilaparvata lugens and Aphis craccivora was evaluated. The compound structure was identified by NMR, HRMS, and single-crystal diffraction. The bioassay results indicated that compound 4-1 (R1 is chloropyridine, R2 is H), 4-2 (R1 is chlorothiazole, R2 is H) and 4-19 (R1 is benzyl, R2 is isopropyl) had the best activity against Nilaparvata lugens (93.5%, 94.1% and 95.5%) at 100?mg/L concentration. The effect of different substituents of R1 or R2 on the activity was studied through the structure–activity relationship. Molecular docking of compounds 4-1 and 4-2 was discussed. Graphic abstract: [Figure not available: see fulltext.].

Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)ethenes

Reactions of 1-amino-2-nitroguanidine with 2-aryl(hetaryl)-1-nitro-1-ethoxycarbonyl(benzoyl)-ethenes proceed via initial formation the aza-Michael product, are accompanied by liberation of nitroacetic ester (or nitroacetophenone), and result in N-aryl(het

β-Nitro-and β-bromo-β-nitrostyrenes in the reactions with aminonitroguanidine

The conditions for the reactions of β-nitro- and β-bromo-β- nitrostyrenes with 1-amino-2- nitroguanidine resulting in the amination products, 1-nitro- and 1-bromo-1-nitro-2-aryl-2-(2-nitroguanidinoamino) ethanes, were found. Under the action of the basic