5426-78-8

Basic information

• Product Name: alpha-ethoxyphenetole
• Synonyms: alpha-ethoxyphenetole;Benzene, (1-ethoxyethoxy)-;1-Ethoxyethyl(phenyl) ether;Phenyl(1-ethoxyethyl) ether;(1-Ethoxyethoxy)benzene;Acetaldehyde ethyl phenyl acetal;NSC 14332
• CAS NO: 5426-78-8
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• EINECS: 226-572-3
• Mol File: 5426-78-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 227°Cat760mmHg
• Flash Point: 79.4°C
• Appearance: /
• Density: 0.979
• CAS DataBase Reference: alpha-ethoxyphenetole(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-ethoxyphenetole(5426-78-8)
• EPA Substance Registry System: alpha-ethoxyphenetole(5426-78-8)

Safety Data

• Hazardous Substances Data: 5426-78-8(Hazardous Substances Data)

Upstream product

• 10477-40-4 1-chloroethyl phenyl ether 
• 109-92-2 ethyl vinyl ether 
• 108-95-2 phenol 
• 766-94-9 vinyl phenyl ether 

Downstream Products

• 17953-97-8 1-phenyl-2-propanol ethyl ether 
• 108-95-2 phenol 
• 873799-83-8 C₁₄H₂₃O₄P 
• 4203-50-3 2-phenoxytetrahydropyran 

Relevant articles and documents

Synthesis of water-soluble phosphinophenol for traceless staudinger ligation

The traceless Staudinger ligation can be mediated in water without organic co-solvents if charged groups render the phenylphosphine reagent water soluble. Here the synthesis of a new water-soluble phosphine is presented based on a diphenylphosphino-phenol reagent. Staudinger ligation with this reagent and azido glycine amide showed conversion of 77%.

Acetonyltriphenylphosphonium bromide and its polymer-supported analogues as catalysts in protection and deprotection of alcohols as alkyl vinyl ethers

Both acetonyltriphenylphosphonium bromide (ATPB, 1) and poly-p-styryldiphenylacetonylphosphonium bromide (A) were effective catalysts in the protection of alcohols as THP, THF, and EE ethers as well as the cleavage of THP, THF, and EE ethers to the corresponding alcohols. They could be applied to 1°, 2° and 3° alcohols, phenol and acid-labile alcohols. Both ATPB and catalyst A are excellent catalysts in the present study. It needed only 1×10-2-1.25×10-2 mol equiv. of the polymer-supported catalyst A in the reactions.