54616-46-5Relevant articles and documents
Reconciling Electrostatic and n→π* Orbital Contributions in Carbonyl Interactions
Adam, Catherine,Borsley, Stefan,Cockroft, Scott L.,Ling, Kenneth B.,Mati, Ioulia K.,Muchowska, Kamila B.,Nichol, Gary S.,Pascoe, Dominic J.,Smolyar, Ivan V.
supporting information, p. 14602 - 14608 (2020/07/06)
Interactions between carbonyl groups are prevalent in protein structures. Earlier investigations identified dominant electrostatic dipolar interactions, while others implicated lone pair n→π* orbital delocalisation. Here these observations are reconciled.
Amidation reaction of carboxylic acid with formamide derivative using SO3?pyridine
Kawano, Shota,Saito, Kodai,Yamada, Tohru
supporting information, p. 584 - 586 (2018/04/12)
The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3?py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.
Palladium-Mediated Site-Selective C-H Radio-iodination
Dubost, Emmanuelle,Babin, Victor,Benoist, Florian,Hébert, Alexandra,Barbey, Pierre,Chollet, Céline,Bouillon, Jean-Philippe,Manrique, Alain,Pieters, Grégory,Fabis, Frédéric,Cailly, Thomas
supporting information, p. 6302 - 6305 (2018/10/02)
The palladium-mediated C-H radio-iodination of arenes using sodium iodide as the primary isotopic source is reported and performed without chemical know-how in 30 min and applied to the synthesis of complex radio-iodinated compounds of biological interest.
