5464-44-8

Basic information

• Product Name: N-PHTHALOYL-DL-METHIONINE
• Synonyms: AKOS BBS-00006532;2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-4-(METHYLTHIO)BUTANOIC ACID;2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-4-(METHYLSULFANYL)BUTANOIC ACID;TIMTEC-BB SBB001859;PHT-DL-MET-OH;PHTHALYL-DL-METHIONINE;PHTHALOYL-DL-METHIONINE;N-PHTHALOYL-DL-METHIONINE
• CAS NO: 5464-44-8
• Molecular Formula: C₁₃H₁₃NO₄S
• Molecular Weight: 279.31
• Mol File: 5464-44-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 492°Cat760mmHg
• Flash Point: 251.4°C
• Appearance: /
• Density: 1.422g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-PHTHALOYL-DL-METHIONINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PHTHALOYL-DL-METHIONINE(5464-44-8)
• EPA Substance Registry System: N-PHTHALOYL-DL-METHIONINE(5464-44-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 5464-44-8(Hazardous Substances Data)

Usage

Description

N-PHTHALOYL-DL-METHIONINE is a chemical compound derived from the amino acid methionine, featuring a phthaloyl group attached to its nitrogen atom. It is recognized for its potential applications in medical treatments and industrial processes due to its ability to chelate heavy metal ions. Known for its relative stability and low toxicity, this compound holds promise in both pharmaceutical and industrial sectors.

Uses

Used in Pharmaceutical Synthesis:
N-PHTHALOYL-DL-METHIONINE is used as a reactant for the synthesis of various pharmaceuticals and organic compounds, leveraging its unique chemical properties to contribute to the development of new medications.
Used in Medical Treatments:
In the medical field, N-PHTHALOYL-DL-METHIONINE is used as a potential treatment for specific conditions such as kidney disease and certain types of cancer, capitalizing on its therapeutic effects that are still under investigation.
Used in Industrial Processes:
N-PHTHALOYL-DL-METHIONINE is utilized as a chelating agent for heavy metal ions in industrial applications, playing a crucial role in environmental remediation and other processes where metal ion management is necessary.
Used in Environmental Remediation:
In environmental applications, N-PHTHALOYL-DL-METHIONINE is used as a remediation agent to chelate and remove heavy metals from contaminated sites, contributing to the cleanup and safety of ecosystems and human habitats.

Upstream product

• 85-44-9 phthalic anhydride 
• 59-51-8 DL-methionine 

Downstream Products

• 55985-04-1 methyl (S)-4-methylsulfanyl-2-phthalimidobutanoate 
• 109541-75-5 methyl 1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)cyclopropanecarboxylate 
• 39739-05-4 methyl-(S)-2-phthalimido-4-methylthiobutanoate 
• 120831-43-8 N,N-phthaloyl-methionine-(N-diphenylacetyl-p-toluidide) 

Relevant articles and documents

Palladium-Catalyzed Decarbonylation of Amino Acid Derivatives via C-C Bond and C-N Bond Dual Activations

A unique decarbonylation of an amino acid derivative catalytic system has been established via palladium-catalyzed C-C bond and C-N bond dual activations. By employing 8-aminoquinoline as the directing group, this transformation has been found to facilitate the high chemoselectivity to decarbonylation of amino acid derivatives rather than intramolecular deamination or cross-dehydrogenative coupling reactions. This method provides a straightforward avenue for constructing diverse functionalized amide compounds in good to excellent yields. We proposed a possible reaction pathway that may go through the C-C bond and C-N bond dual activations on the basis of the mechanistic studies.