54641-19-9

Basic information

• Product Name: sodium (S)-2-hydroxy-3-methylbutyrate
• Synonyms: sodium (S)-2-hydroxy-3-methylbutyrate;(2S)-2-Hydroxy-3-methylbutyric acid sodium salt;[S,(-)]-2-Hydroxy-3-methylbutyric acid sodium salt
• CAS NO: 54641-19-9
• Molecular Formula: C₅H₉O₃*Na
• Molecular Weight: 140.11293
• EINECS: 259-268-4
• Mol File: 54641-19-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: sodium (S)-2-hydroxy-3-methylbutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium (S)-2-hydroxy-3-methylbutyrate(54641-19-9)
• EPA Substance Registry System: sodium (S)-2-hydroxy-3-methylbutyrate(54641-19-9)

Safety Data

• Hazardous Substances Data: 54641-19-9(Hazardous Substances Data)

Usage

Description

Sodium (S)-2-hydroxy-3-methylbutyrate, also known as (S)-2-Hydroxy-3-methylbutyric Acid Sodium Salt, is an organic sodium salt derived from (S)-2-hydroxy-3-methylbutyric acid. It is a white crystalline solid that is soluble in water and has a molecular formula of C5H9NaO3. sodium (S)-2-hydroxy-3-methylbutyrate is known for its unique chemical properties and potential applications in various industries.

Uses

Used in Chemical Synthesis:
Sodium (S)-2-hydroxy-3-methylbutyrate is used as a chemical intermediate for the preparation and reaction with benzyl bromide. This reaction is crucial in the synthesis of various organic compounds and pharmaceuticals, as it allows for the formation of new carbon-carbon bonds and the creation of complex molecular structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, sodium (S)-2-hydroxy-3-methylbutyrate is used as a building block for the development of new drugs. Its unique chemical structure makes it a valuable component in the synthesis of various therapeutic agents, particularly those targeting metabolic disorders and neurological conditions.
Used in Flavor and Fragrance Industry:
Sodium (S)-2-hydroxy-3-methylbutyrate is also utilized in the flavor and fragrance industry as a key ingredient in the creation of natural and artificial flavors. Its distinct chemical properties contribute to the development of unique and complex aromas, enhancing the sensory experience of various consumer products.
Used in Cosmetics Industry:
In the cosmetics industry, sodium (S)-2-hydroxy-3-methylbutyrate is employed as an active ingredient in the formulation of skincare and hair care products. Its ability to interact with biopolymers and macromolecules makes it a promising candidate for improving the efficacy of these products, promoting skin health and hair growth.
Used in Food Industry:
Sodium (S)-2-hydroxy-3-methylbutyrate is used in the food industry as a flavor enhancer and additive. Its unique taste and aroma properties contribute to the enhancement of the overall flavor profile of various food products, making them more appealing to consumers.

InChI:InChI=1/C5H10O3.Na/c1-3(2)4(6)5(7)8;/h3-4,6H,1-2H3,(H,7,8);/q;+1/p-1/t4-;/m0./s1

Upstream product

• 3715-29-5 sodium 3-methyl-2-oxobutyrate 
• 72-18-4 L-valine 

Downstream Products

• 65138-05-8 (S)-2-hydroxy-3-methylbutyric acid benzyl ester 
• 125150-46-1 (S)-1-carboxy-2-methylpropyl 4-(trans-4-heptylcyclohexyl)benzoate 
• 125177-19-7 (S)-1-carbamoyl-2-methylpropyl 4'-nonylbiphenyl-4-carboxylate 
• 118827-21-7 (S)-1-carbamoyl-2-methylpropyl 4'-octoxybiphenyl-4-carboxylate 
• 125150-57-4 (S)-1-carbamoyl-2-methylpropyl 3-(4'-octoxybiphenyl-4-yl)propanoate 
• 125150-60-9 (S)-1-carbamoyl-2-methylpropyl 4-(4-hexoxybenzoyloxy)benzoate 
• 125150-52-9 (S)-1-carboxy-2-methylpropyl 4-(4-hexoxybenzoyloxy)benzoate 
• 125150-37-0 (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4-(trans-4-heptylcyclohexyl)benzoate 
• 125150-36-9 (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4'-nonylbiphenyl-4-carboxylate 
• 125150-39-2 (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4-(5-heptylpyrimidin-2-yl)benzoate 
• 118827-19-3 (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4'-octocxybiphenyl-4-carboxylate 
• 125150-50-7 (S)-1-carboxy-2-methylpropyl trans-4-(4'-octoxybiphenyl-4-yl)cyclohexanecarboxylate 
• 125150-58-5 (S)-1-carbamoyl-2-methylpropyl trans-4-(4'-octoxybiphenyl-4-yl)cyclohexanecarboxylate 
• 125150-40-5 (S)-1-(benzyloxycarbonyl)-2-methylpropyl 4'-octoxybiphenyl-4-ylethanoate 

Relevant articles and documents

A new family of D-2-hydroxyacid dehydrogenases that comprises D-mandelate dehydrogenases and 2-ketopantoate reductases

The gene for the D-mandelate dehydrogenase (DManDH) of Enterococcus faecalis IAM10071 was isolated by means of an activity staining procedure and PCR and expressed in Escherichia coli cells. The recombinant enzyme exhibited high catalytic activity toward various 2-ketoacid substrates with bulky hydrophobic side chains, particularly C3-branched substrates such as benzoylformate and 2-ketoisovalerate, and strict coenzyme specificity for NADH and NAD+. It showed marked sequence similarity with known NADP-dependent 2-ketopantoate reductases (KPR). These results indicate that together with KPR, D-ManDH constitutes a new family of D-2-hydroxyacid dehydrogenases that act on C3-branched 2-ketoacid substrates with various specificities for coenzymes and substrates.