5470-28-0 Usage
Description
Diethyl piperazine-1,4-dicarboxylate is a chemical compound with the molecular formula C10H18N2O4. It is a versatile intermediate in the synthesis of pharmaceuticals, particularly for the production of antihistamines and antipsychotic drugs. diethyl piperazine-1,4-dicarboxylate has been found to possess potential therapeutic effects, such as antitumor and antiviral activities. Additionally, it serves as a corrosion inhibitor in metalworking fluids and as a stabilizer in PVC resin. Diethyl piperazine-1,4-dicarboxylate is considered to have low toxicity and is not classified as a hazardous substance by regulatory agencies.
Uses
Used in Pharmaceutical Industry:
Diethyl piperazine-1,4-dicarboxylate is used as an intermediate in the synthesis of various pharmaceuticals, including antihistamines and antipsychotic drugs, due to its versatile chemical properties and potential therapeutic effects.
Used in Metalworking Fluids:
Diethyl piperazine-1,4-dicarboxylate is used as a corrosion inhibitor in metalworking fluids, helping to prevent the degradation of metal surfaces during manufacturing processes.
Used in PVC Resin:
Diethyl piperazine-1,4-dicarboxylate is used as a stabilizer in PVC resin, contributing to the material's durability and resistance to degradation.
Check Digit Verification of cas no
The CAS Registry Mumber 5470-28-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,7 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5470-28:
(6*5)+(5*4)+(4*7)+(3*0)+(2*2)+(1*8)=90
90 % 10 = 0
So 5470-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H18N2O4/c1-3-15-9(13)11-5-7-12(8-6-11)10(14)16-4-2/h3-8H2,1-2H3
5470-28-0Relevant articles and documents
Novel piperazine based compounds as potential inhibitors for SARS-CoV-2 Protease Enzyme: Synthesis and molecular docking study
El-atawy, Mohamed,El-sadany, Samer K.,Hamed, Ezzat A.,Mosa, Tawfik M.,Omar, Alaa Z.
, (2021)
Structurally diverse piperazine-based compounds hybrid with thiadiazole, isatin or with sulfur/nitrogen, functionalities were synthesized. The structures of the new compounds were established based on their spectral data and elemental analysis. The physicochemical, bioactivity scores and pharmacokinetic behavior of all the prepared ligands were evaluated using in silico computational tools. The new piperazine ligands have been screened for their inhibition activity against SARS-CoV-2 protease enzyme using molecular docking analysis. The docking studies showed that all the ligands have been docked with negative dock energy onto the target protease protein. Moreover, Molecular interaction studies revealed that SARS-CoV-2 protease enzyme had strong hydrogen bonding interactions with piperazine ligands. The present in silico study thus, provided some guidance to facilitate drug design targeting the SARS-CoV-2 main protease.
N-desmethyl analogues of (+)-4-dimethylamino-2,α-dimethylphenethylamine. Synthesis and configurational relationships
Florvall,Persson
, p. 141 - 146 (2007/10/02)
-