5470-75-7 Usage
Description
6-chloroquinolin-8-amine, also known as 6-Chloro-8-aminoquinoline, is a di-substituted quinoline derivative characterized by the presence of a chlorine atom at the 6th position and an amino group at the 8th position in its molecular structure. 6-chloroquinolin-8-amine holds potential applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
6-chloroquinolin-8-amine is used as a chemical intermediate for the synthesis of fungitoxic analogs, which are essential in developing antifungal medications. These analogs target and inhibit the growth of fungi, providing a treatment option for various fungal infections.
Used in Chemical Synthesis:
In the field of chemical synthesis, 6-chloroquinolin-8-amine serves as a key building block for creating more complex molecules with potential applications in different industries, such as agriculture, pharmaceuticals, and materials science. Its unique structure allows for further functionalization and modification to develop novel compounds with desired properties.
Check Digit Verification of cas no
The CAS Registry Mumber 5470-75-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,7 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5470-75:
(6*5)+(5*4)+(4*7)+(3*0)+(2*7)+(1*5)=97
97 % 10 = 7
So 5470-75-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2/c10-7-4-6-2-1-3-12-9(6)8(11)5-7/h1-5H,11H2
5470-75-7Relevant articles and documents
-
Gilman et al.
, p. 1577 (1946)
-
Visible Light-Promoted Photocatalytic C-5 Carboxylation of 8-Aminoquinoline Amides and Sulfonamides via a Single Electron Transfer Pathway
Sen, Chiranjit,Sahoo, Tapan,Singh, Harshvardhan,Suresh, Eringathodi,Ghosh, Subhash Chandra
, p. 9869 - 9896 (2019/08/20)
An efficient photocatalytic method was developed for the remote C5-H bond carboxylation of 8-aminoquinoline amide and sulfonamide derivatives. This methodology uses in situ generated ?CBr3 radical as a carboxylation agent with alcohol and is further extended to a variety of arenes and heteroarenes to synthesize the desired carboxylated product in moderate-to-good yields. The reaction proceeding through a single electron transfer pathway was established by a control experiment, and a butylated hydroxytoluene-trapped aryl radical cation intermediate in high-resolution mass spectrometry was identified.
Piperazine-piperidine antagonists and agonists of the 5-HT1A receptor
-
Page/Page column 55, (2010/11/25)
The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agonists. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction.