54917-66-7Relevant articles and documents
Preparation of 5, 6, 4 '-three hydroxy flavone-7-0-D-glucuro method
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Paragraph 0068; 0069, (2017/02/24)
The invention relates to the field of drug synthesis and discloses a method for preparing 5,6,4'-trihydroxy flavone-7-0-D-glucuronic acid. The method is characterized by taking 5,6,7,4'-tetrahydroxy flavone as a raw material, adopting a brand-new syntheti
METHOD FOR PREPARING 5,6,4'-TRIHYDROXYFLAVONE-7-0-D-GLUCURONIC ACID
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Paragraph 0048, (2015/03/13)
The present invention relates to the field of drug synthesis. Disclosed is a method for preparing 5,6,4'-trihydroxyflavone-7-O-D-glucuronic acid. The method for preparing 5,6,4'-trihydroxyflavone-7-O-D-glucuronic acid of the present invention uses 5,6,7,4'-tetrahydroxyflavone as a raw material and adopts a new synthetic route to obtain high-purity 5,6,4'-trihydroxyflavone-7-O-D-glucuronic acid through an acylation reaction, a glycosylation reaction, and two-step hydrolysis. The preparing method of the present invention has a short synthetic route, low cost, and high reaction yield, the product is easy for purification, and the method is applicable to industrial production of 5,6,4'-trihydroxyflavone-7-O-D-glucuronic acid.