55029-05-5

Basic information

• Product Name: Dihydrobetulin
• CAS NO: 55029-05-5
• Molecular Weight: 444.742
• Mol File: 55029-05-5.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Dihydrobetulin(CAS DataBase Reference)
• NIST Chemistry Reference: Dihydrobetulin(55029-05-5)
• EPA Substance Registry System: Dihydrobetulin(55029-05-5)

Safety Data

• Hazardous Substances Data: 55029-05-5(Hazardous Substances Data)

Upstream product

• 473-98-3 betulin 
• 1072913-62-2 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol 
• 1721-69-3 betulin diacetate 
• 43124-92-1 3β,28-Diacetoxylupane 
• 1721-69-3 betulin diacetate 
• 81346-04-5 3β,28-lupanediol 28-acetate 
• 79875-65-3 6β,28-dihydroxy-3-oxolup-20(29)-ene 
• 79875-75-5 6β,28-diacetoxylup-20(29)-en-3-one 
• 54145-78-7 (1S,3a5,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-isopropyl-5a,5b,8,8,11a-pentamethyl-9-oxoicosahydro-1H-cyclopenta[a]chrysene-3a-carbaldehyde 
• 43124-92-1 (?)-3β,28-diacetoxydihydrobetulin 

Downstream Products

• 25576-27-6 Lupanon-⁽³⁾-carbonsaeure-⁽²⁸⁾ 
• 43124-92-1 (?)-3β,28-diacetoxydihydrobetulin 
• 25576-27-6 3-oxolupan-28-ic acid 
• 1007345-51-8 C₄₉H₇₆N₂O₅ 
• 20066-05-1 methyl dihydrobetulonate 
• 134501-93-2 17α(H)-28-Norlupane 
• 134501-93-2 17β(H)-28-Norlupane 
• 134502-04-8 3-Oxolupane tosylhydrazone 
• 464-99-3 Lupane 
• 3186-72-9 3-Oxolupane 
• 3186-86-5 3β-Hydroxy-28-lupane 
• 38736-78-6 dihydrobetulinic acid 
• 81346-04-5 3β,28-lupanediol 28-acetate 
• 1393571-37-3 3-O,28-O-diphthaloyl dihydrobetulin 

Relevant articles and documents

Preparation of a 24-nor-1,4-dien-3-one triterpene derivative from betulin: A new route to 24-nortriterpene analogues

A new route to 24-nortriterpene derivatives with 2-hydroxy-δ1,4-cyclohexadieny-3-one A-rings from triterpene precursors has been demonstrated beginning with betulin to prepare derivatives of betulinic acid. The key steps in the transformation are a Suarez cleavage of the A-ring with a subsequent SM12-mediated pinacol-type coupling to reclose the A-ring following removal of the C-24 carbon by oxidative cleavage.

Synthesis and Antimicrobial Activity of Dihydrobetulin N-Acetylglucosaminides

Dihydrobetulin N-acetylglucosaminides were synthesized for the first time. A study of their antimicrobial activity against a standard set of Gram-positive and Gram-negative bacteria and fungi showed highly selective bacteriostatic activity for glycosides 9 and 13 against Staphylococcus aureus ATCC 209p.

EXTENDED BETULINIC ACID ANALOGS

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represen