550372-56-0

Basic information

• Product Name: 1,3-Dioxolo[4,5-g]quinoline-8-carboxamide, N-(2-iodo-4,5-dimethoxyphenyl)-
• CAS NO: 550372-56-0
• Molecular Formula: C19H15IN2O5
• Molecular Weight: 478.243
• Mol File: 550372-56-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolo[4,5-g]quinoline-8-carboxamide, N-(2-iodo-4,5-dimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolo[4,5-g]quinoline-8-carboxamide, N-(2-iodo-4,5-dimethoxyphenyl)-(550372-56-0)
• EPA Substance Registry System: 1,3-Dioxolo[4,5-g]quinoline-8-carboxamide, N-(2-iodo-4,5-dimethoxyphenyl)-(550372-56-0)

Safety Data

• Hazardous Substances Data: 550372-56-0(Hazardous Substances Data)

Upstream product

• 550372-54-8 4,5-dimethoxy-2-iodoaniline 
• 550372-53-7 N-(2-iodo-4,5-dimethoxyphenyl)acetamide 
• 693263-05-7 4-formyl-6,7-methylenedioxyquinoline 
• 51048-62-5 4-methyl-6,7-methylenedioxyquinoline 
• 881-70-9 3',4'-dimethoxyacetanilide 
• 60597-63-9 6,7-methylenedioxyquinoline-4-carboxylic acid 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 

Downstream Products

• 791130-75-1 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(piperidin-1-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 884850-50-4 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(morpholin-4-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 884850-52-6 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N,N-dibenzylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 884850-49-1 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(4-methylpiperidin-1-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 884850-60-6 13-[2-(benzyl-methyl-amino)-ethyl]-2,3-dimethoxy-13H-8,10-dioxa-6,13-diaza-cyclopenta[b]chrysen-12-one 
• 884850-58-2 13-(2-dibenzylamino-ethyl)-2,3-dimethoxy-13H-8,10-dioxa-6,13-diaza-cyclopenta[b]chrysen-12-one 
• 884850-51-5 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(1-methylpyrrolidin-2-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 884850-53-7 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N-benzyl-N-methylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 884850-48-0 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(pyrrolidin-1-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 791130-73-9 6,7-methylenedioxyquinoline-4-carboxylic acid N-[3-(N,N-dimethylamino)propyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 791130-74-0 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N,N-diethylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 550372-57-1 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N,N-dimethylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 

Relevant articles and documents

6-Substituted 6H-dibenzo[c,h][2,6]naphthyridin-5-ones: Reversed lactam analogues of ARC-111 with potent topoisomerase I-targeting activity and cytotoxicity

6-Substituted 8,9-dimethoxy-2,3-methylenedioxy-6H-dibenzo[c,h][2,6] naphthyridin-5-ones were synthesized and evaluated for topoisomerase I-targeting activity and cytotoxicity. Several of these reversed lactam analogues of ARC-111 exhibited exceptional cyt