551963-98-5

Basic information

• Product Name: 2-(3-methoxy-2-methyl-phenyl)-3-oxa-1-aza-spiro[4.4]non-1-en-4-one
• Synonyms: 2-(3-methoxy-2-methyl-phenyl)-3-oxa-1-aza-spiro[4.4]non-1-en-4-one
• CAS NO: 551963-98-5
• Molecular Weight: 259.305
• Mol File: 551963-98-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3-methoxy-2-methyl-phenyl)-3-oxa-1-aza-spiro[4.4]non-1-en-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-methoxy-2-methyl-phenyl)-3-oxa-1-aza-spiro[4.4]non-1-en-4-one(551963-98-5)
• EPA Substance Registry System: 2-(3-methoxy-2-methyl-phenyl)-3-oxa-1-aza-spiro[4.4]non-1-en-4-one(551963-98-5)

Safety Data

• Hazardous Substances Data: 551963-98-5(Hazardous Substances Data)

Upstream product

• 24487-91-0 3-methoxy-2-methylbenzoyl chloride 
• 52-52-8 1-amino-1-cyclopentanecarboxylic acid 

Downstream Products

• 551964-01-3 3-methoxy-N-[1-(methoxy-methyl-carbamoyl)-cyclopentyl]-2-methyl-benzamide 
• 551964-08-0 N-(1-formyl-cyclopentyl)-3-methoxy-2-methyl-benzamide 
• 551964-05-7 N-(1-hydroxymethyl-cyclopentyl)-3-methoxy-2-methyl-benzamide 

Relevant articles and documents

Synthesis and SAR of α-acylaminoketone ligands for control of gene expression

A lead discovery library and a follow-up focused library of α-acylaminoketones were designed based on known dibenzoylhydrazine ecdysone agonists, including GS-E. The compounds were assayed in mammalian cells expressing the ecdysone receptor from Bombyx mori for their ability to cause expression of a reporter gene downstream of an ecdysone response element. The most potent α-acylaminoketones were comparable to GS-E in this assay.