55242-55-2 Usage
Description
Propentofylline, also known by its brand name Hextol, is a nootropic drug with various pharmacological properties. It is an off-white solid and is primarily indicated for the treatment of cerebrovascular disorders. Other potential indications under investigation include senile dementia, stroke, and hypoxia.
Uses
1. Used in Pharmaceutical Industry:
Propentofylline is used as a c-AMP phosphodiesterase inhibitor for its ability to increase the levels of cyclic adenosine monophosphate (c-AMP) in cells, which can lead to various beneficial effects on cellular function and signaling.
2. Used in Neurological Applications:
Propentofylline is used as a nerve growth factor stimulator to promote the growth and maintenance of nerve cells, which can be beneficial in treating conditions related to nerve damage or degeneration.
3. Used in Cellular Metabolism:
Propentofylline is used as an adenosine transport inhibitor, which can help regulate the levels of adenosine in the body. This can have various effects on cellular metabolism and function.
4. Used in Adenosine Receptor Modulation:
Propentofylline is used as a non-selective adenosine receptor antagonist, which means it can block the action of adenosine at its receptors. This can have potential therapeutic effects in various conditions, including those related to inflammation and immune response.
5. Used in Cognitive Enhancement:
Propentofylline is used as a nootropic to enhance cognitive function and improve memory, attention, and overall brain health. It is particularly useful in the treatment of cerebrovascular disorders and is being investigated for its potential benefits in conditions such as senile dementia, stroke, and hypoxia.
Originator
Hoechst AG (W.Germany)
Biochem/physiol Actions
c-AMP phosphodiesterase inhibitor; nerve growth factor stimulator; adenosine transport inhibitor; non-selective adenosine receptor antagonist.
Check Digit Verification of cas no
The CAS Registry Mumber 55242-55-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,2,4 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 55242-55:
(7*5)+(6*5)+(5*2)+(4*4)+(3*2)+(2*5)+(1*5)=112
112 % 10 = 2
So 55242-55-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N4O3/c1-4-8-18-10-16-13-12(18)14(21)19(15(22)17(13)3)9-6-5-7-11(2)20/h10H,4-9H2,1-3H3
55242-55-2Relevant articles and documents
Combination preparation for use in dementia
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, (2008/06/13)
The invention relates to a composition which is a pharmaceutical combination preparation comprising a compound which has an acetylcholinesterase-inhibitory action or exhibits muscarinergic action and a compound which increases the endogenous extracellular adenosine level, wherein the combination preparation is suitable for the treatment of dementia. The invention further relates to a process for the production of the combination preparation. The invention additionally relates to a process for treating patients in need of suitable therapy with the combination preparation.
Xanthine derivatives for the treatment of secondary nerve cell damage and functional disorders after cranio-cerebral traumas
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, (2008/06/13)
The use of xanthine derivatives for the treatment of secondary nerve cell damage and functional disorders after cranio-cerebral traumas (CCT) The use of xanthine derivatives of the formula I STR1 and of their physiologically tolerable salts, in which R1 is oxoalkyl, hydroxyalkyl or alkyl, R2 is hydrogen or alkyl and R3 is hydrogen, alkyl, oxoalkyl or an alkyl having up to 6 carbon atoms, whose carbon chain is interrupted by an oxygen atom, for the production of pharmaceuticals for the treatment of disorders which can occur after cranio-cerebral traumas is described.
Pharmaceutical combination preparations containing cephalosporin and xanthine derivatives and their use
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, (2008/06/13)
Pharmaceutical combination preparations containing cefotaxime and at least one xanthine derivative are suitable for the treatment of bacterial infectious diseases and for the treatment of septic shock.
