55242-68-7

Basic information

• Product Name: 7-ethyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione
• CAS NO: 55242-68-7
• Molecular Formula: C₈H₁₀N₄O₂
• Molecular Weight: 194.1906
• Mol File: 55242-68-7.mol
• Article Data: 3

Chemical Properties

• Density: 1.51g/cm³
• Refractive Index: 1.702
• CAS DataBase Reference: 7-ethyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-ethyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione(55242-68-7)
• EPA Substance Registry System: 7-ethyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione(55242-68-7)

Safety Data

• Hazardous Substances Data: 55242-68-7(Hazardous Substances Data)

Upstream product

• 23043-88-1 7-ethyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 
• 115377-55-4 1-ethyl-4-(N-methylamino)-1H-imidazole-5-carboxamide 
• 1076-22-8 3-methylxanthine 
• 75-03-6 ethyl iodide 

Downstream Products

• 139928-01-1 1-Benzyl-7-ethyl-3-methyl-3,7-dihydro-purine-2,6-dione 
• 55242-59-6 7-ethyl-3-methyl-1-(5-oxohexyl)-1H-purine-2,6(3H,7H)-dione 

Relevant articles and documents

Hydroxypurine compound and use thereof

The invention discloses a hydroxypurine compound and a use of the hydroxypurine compound as a PDE2 or TNFa inhibitor and concretely discloses a compound shown in the formula (I) and its tautomer or pharmaceutically acceptable salt.

A FACILE CONVERSION OF THE 1-METHYL GROUP TO THE 1-AMINO GROUP OF XANTHINE DERIVATIVES

A facile conversion of the 1-methyl group to the 1-amino group of caffeine and its analogues was carried out by the reaction with hydrazine hydrate: Refluxing of caffeine (Ia) with a large amount of hydrazine hydrate (30 eq. mole) without any other solvents gave 1-amino-3,7-dimethylxanthine (IIa) in 40percent yield.Similarly the reaction of 7-substituted 1,3-dimethylxanthines (Ib,Id-f) with hydrazine hydrate gave 7-substituted 1-amino-3-methylxanthines (IIb, IId-f) in 28-42percent yield.Deamination of these 7-substituted 1-amino-3-methylxanthines (IIa-b, IId-f) gave the corresponding theobromine derivatives (IVa-b, IVd-f) in 90-96percent yield.