55245-48-2

Basic information

• Product Name: 1H-Imidazole-1-carboxamide, N-(1-methylethyl)-N-(phenylmethyl)-
• CAS NO: 55245-48-2
• Molecular Formula: C14H17N3O
• Molecular Weight: 243.308
• Mol File: 55245-48-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole-1-carboxamide, N-(1-methylethyl)-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-1-carboxamide, N-(1-methylethyl)-N-(phenylmethyl)-(55245-48-2)
• EPA Substance Registry System: 1H-Imidazole-1-carboxamide, N-(1-methylethyl)-N-(phenylmethyl)-(55245-48-2)

Safety Data

• Hazardous Substances Data: 55245-48-2(Hazardous Substances Data)

Upstream product

• 102-97-6 Benzyl-isopropyl-amin 
• 530-62-1 1,1'-carbonyldiimidazole 

Relevant articles and documents

Carbamoylimidazolium and thiocarbamoylimidazolium salts: Novel reagents for the synthesis of ureas, thioureas, carbamates, thiocarbamates and amides

Carbamoylimidazolium salts act as efficient N,N-disubstituted carbamoylating reagents. These salts are readily prepared by the sequential treatment of secondary amines with N,N′-carbonyldiimidazole (CDI) and iodomethane. The carbamoylimidazolium salts are more efficient carbamoyl transfer reagents than the intermediate carbamoylimidazoles, as a result of the 'imidazolium' effect. Kinetic studies on the base promoted hydrolysis of both carbamoylimidazoles and carbamoylimidazolium salts reveal over a hundred-fold rate acceleration. The salts react with amines, thiols, phenols/alcohols, and carboxylic acids in high yields, without the need for subsequent chromatographic purification of the products, producing ureas, thiocarbamates, carbamates, and amides, respectively. Analogous thiocarbamoylimidazolium salts were also synthesized from secondary amines and N,N′-thiocarbonyldiimidazole (TCDI), followed by methylation with iodomethane.