554423-67-5Relevant articles and documents
Thiourea-catalyzed asymmetric michael addition of activated methylene compounds to α,β-unsaturated imides: Dual activation of imide by intra- and intermolecular hydrogen bonding
Inokuma, Tsubasa,Hoashi, Yasutaka,Takemoto, Yoshiji
, p. 9413 - 9419 (2007/10/03)
A thiourea-catalyzed asymmetric Michael addition of activated methylene compounds to α,β-unsaturated imides derived from 2-pyrrolidinone and 2-methoxybenzamide has been developed. In the case of 2-pyrrolidinone derivatives, the reaction with malononitrile