55540-36-8Relevant articles and documents
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one derivatives
Grande, Fedora,Brizzi, Antonella,Garofalo, Antonio,Aiello, Francesca
, p. 9951 - 9956 (2013/11/06)
The hitherto unknown lactone 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one and six of its substituted derivatives have been prepared by active manganese dioxide promoted oxidative cyclization of the corresponding 2-(1H-pyrrol-1-yl)benzoic acids, under mild conditions, in moderate yields. The method was successfully extended to the cyclization of some ortho-(1H-pyrrol-1-yl)heteroaryl carboxylic acids and 2-(1H-indol-1-yl)benzoic acids.
Oral hypoglycemic agents: 1(2 carboxyphenyl)pyrroles
Sugihara,Matsumoto,Hamuro,Kawamatsu
, p. 1560 - 1563 (2007/10/06)
A series of 1 (2 carboxyphenyl) pyrroles and their cyclized derivatives, pyrrolo [1,2 a]indoles, was synthesized and screened for hypoglycemic activity in rats. 1 (2 Carboxy 3 chlorophenyl) pyrrole was the most active, but had side effects.