5556-84-3 Usage
Description
2,3,5-Trimethoxybenzaldehyde is an organic compound characterized by its aromatic ring structure with three methoxy groups at the 2nd, 3rd, and 5th positions, and an aldehyde group at the 1st position. It is a versatile chemical intermediate with a wide range of applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
2,3,5-Trimethoxybenzaldehyde is used as a starting reagent for the preparation of imine derivatives, which might exhibit glycosidase inhibitory properties. These inhibitors are essential in the development of drugs targeting various diseases, including diabetes and obesity, by modulating the activity of glycosidase enzymes.
2,3,5-Trimethoxybenzaldehyde is also used as a starting reagent for the preparation of phenylalkylamine analogs with psychoactive properties. These analogs have potential applications in the development of medications for the treatment of neurological and psychiatric disorders, such as depression, anxiety, and schizophrenia.
Used in Chemical Synthesis:
2,3,5-Trimethoxybenzaldehyde serves as a starting reagent for the preparation of flavonoids, a class of natural compounds with diverse biological activities. Flavonoids are found in many plants and have been extensively studied for their antioxidant, anti-inflammatory, and anticancer properties. The synthesis of flavonoids using 2,3,5-trimethoxybenzaldehyde can contribute to the development of novel therapeutic agents and nutraceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 5556-84-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,5 and 6 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5556-84:
(6*5)+(5*5)+(4*5)+(3*6)+(2*8)+(1*4)=113
113 % 10 = 3
So 5556-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O4/c1-12-8-4-7(6-11)10(14-3)9(5-8)13-2/h4-6H,1-3H3
5556-84-3Relevant articles and documents
An Improved Preparation of the p-Tropoquinone Mono- and Diacetals by Thallium(III) Nitrate Oxidation of 2-Alkoxy-5-hydroxytropones
Takeshita, Hitoshi,Mori, Akira,Isayama, Yasutoshi
, p. 1678 - 1682 (1985)
The thallium(III) nitrate-oxidation of 2-alkoxy-5-hydroxytropones gave, in good yields, the mono- and diacetals of tropoquinones, which can be used for the introduction of oxygen functions to the seven-membered nucleus and preparation of the substituted t
Attempt to synthesize 2,3,5,4′-tetrahydroxystilbene derived from 2,3,5,4′-tetrahydroxystilbene-2-O-β-glucoside (THSG)
Tamura, Masafumi,Koshibe, Yuhei,Kaji, Kiho,Ueda, Jun-Ya,Shirataki, Yoshiaki
, p. 122 - 125 (2015/02/19)
An attempt to synthesize aglycone 1 derived from 2,3,5,4′-tetrahydroxystilbene-2-O-β-glucoside (THSG) via the Wittig reaction and Mizoroki-Heck reaction is described. In the Wittig protocol, 2,3,5,4′-tetramethoxystilbene 2 was obtained. Additionally, a palladium-catalyzed Mizoroki-Heck reaction strategy yielded 2-aryl-2,3-dihydrobenzofuran 13 instead of derivative 12 in good yield.
Synthesis of 2-Methoxystypandrone: Comments on the Structure of Ventilaginone
Hughes, Andrew B.,Sargent, Melvyn V.
, p. 449 - 452 (2007/10/02)
The structure of 2-methoxystypandrone a naphthoquinone isolated from Polygonum cuspidatum, Rhamnus fallax, and Ventilago calyculata is confirmed by synthesis as 6-acetyl-5-hydroxy-2-methoxy-7-methylnaphthalene-1,4-dione (1).The structure proposed for ventilaginone, an unusual naphthalene isolated from Ventilago maderaspatana, 8,9-dimethoxy-5-methylnaphtho-1,3-dioxin-4-yl methyl ketone (17), is shown by synthesis to be erroneous.Alternative structures are considered.
