55577-80-5

Basic information

• Product Name: D-6-methoxy-α-methyl-2-naphthaleneacetic acid sodium salt
• Synonyms: D-6-methoxy-α-methyl-2-naphthaleneacetic acid sodium salt
• CAS NO: 55577-80-5
• Molecular Weight: 252.245
• Mol File: 55577-80-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: D-6-methoxy-α-methyl-2-naphthaleneacetic acid sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: D-6-methoxy-α-methyl-2-naphthaleneacetic acid sodium salt(55577-80-5)
• EPA Substance Registry System: D-6-methoxy-α-methyl-2-naphthaleneacetic acid sodium salt(55577-80-5)

Safety Data

• Hazardous Substances Data: 55577-80-5(Hazardous Substances Data)

Upstream product

• 27602-76-2 2-(6-methoxy-2-naphthyl)propanal oxime 
• 23981-80-8 naproxen 
• 22204-53-1 (2S)-2-(6-methoxy(2-naphthyl))propanoic acid 

Downstream Products

• 158877-62-4 2-(6-Methoxy-naphthalen-2-yl)-propionic acid (benzoyl-ethoxycarbonylmethyl-amino)-methyl ester 
• 22204-53-1 (2S)-2-(6-methoxy(2-naphthyl))propanoic acid 
• 110599-10-5 2-hydroxyethyl 2-(6-methoxy-2-naphthyl)propanoate 

Relevant articles and documents

NAPROXCINOD PROCESS AND SOLID DISPERSION

Processes for the preparation of naproxcinod and its purification, solid dispersions of naproxcinod with a pharmaceutically acceptable carrier, and processes for making dispersions. Also provided is crystalline 2-(S)-(4-chlorobutyl)-2-(6-methoxy-2-naphthyl)-propanoate and methods for its preparation.

Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation

This invention is directed to nitric esters of derivatives of propionic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid, 5-benzoyl-1,2-dihydro-3H-pyrrolo?1,2-a!pyrrole-1-carboxylic acid, 6-methoxy-2-napthylacetic acid, characterized in that they have the following general formula: STR1 These nitric ester derivatives may be formulated into pharmaceutical compositions and administered for their anti-inflammatory and/or analgesic activity.

Process for the resolution of (+)-6-methoxy-α-methyl-2-naphthaleneacetic acid into the corresponding enantiomers

An improved process for the resolution of (+)-6-methoxy-α-methyl-2-naphthaleneacetic acid into the corresponding enantiomers by using L-threo-(+)-2-amino-1-(4-nitrophenyl)-1,3-propanediol and L-threo-(+)-2-amino-1-(4-methylmercaptophenyl)-1,3-propanediol.