5571-36-8 Usage
Description
Estradiene dione-3-keta, also known as 3-keto-estradiol, is a synthetic steroidal compound derived from estrone. It is an off-white solid with unique chemical properties that make it a versatile intermediate in the pharmaceutical industry. Its structure allows for various modifications and applications in different fields.
Uses
Used in Pharmaceutical Industry:
Estradiene dione-3-keta is used as an intermediate for the synthesis of Mifepristone, a drug with antiprogestational and antiglucocorticoid properties. It plays a crucial role in the development of medications for various medical conditions, including reproductive health and hormone-related disorders.
Used in Steroidal Spirooxazole Synthesis:
Estradiene dione-3-keta is also utilized as a key component in the production of steroidal spirooxazoles. These compounds have potential applications in the treatment of various diseases and conditions due to their unique structural and functional properties.
Used in Hormone Research:
Due to its structural similarity to natural hormones, Estradiene dione-3-keta is used in research to study the effects of hormones on the human body. This helps in understanding the mechanisms of hormone action and developing new therapeutic strategies for hormone-related disorders.
Used in Drug Development:
Estradiene dione-3-keta serves as a valuable compound in the development of new drugs with potential applications in various therapeutic areas. Its unique chemical properties allow for the creation of novel molecules with improved pharmacological profiles and targeted effects.
Check Digit Verification of cas no
The CAS Registry Mumber 5571-36-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,7 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5571-36:
(6*5)+(5*5)+(4*7)+(3*1)+(2*3)+(1*6)=98
98 % 10 = 8
So 5571-36-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H26O3/c1-19-8-6-15-14-7-9-20(22-10-11-23-20)12-13(14)2-3-16(15)17(19)4-5-18(19)21/h6,16-17H,2-5,7-12H2,1H3/t16-,17+,19+/m1/s1
5571-36-8Relevant articles and documents
11,21-Bisphenyl-19-norpregnane derivatives are selective antiglucocorticoids
Gebhard,Van Der Voort,Schuts,Schoonen
, p. 2229 - 2234 (2007/10/03)
An efficient eight-step synthesis of 11,21-bisphenyl-19-norpregnane derivatives (10) starting from 19-norandrosta-4,9-diene-3,17-dione (5) is described. It is shown that specific combinations of polar substitutions on the 11- and the 21-phenylring in compounds (10) lead to selective antiglucocorticoids with relative high binding to the glucocorticoid receptor and almost negligible binding to the progesterone receptor.