56026-56-3Relevant articles and documents
Design and synthesis of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced protein phosphatase 2A-activating profile and neuroprotection
Lajarín-Cuesta, Rocío,Arribas, Raquel L.,Nanclares, Carmen,García-Frutos, Eva M.,Gandía, Luis,de los Ríos, Cristóbal
, p. 294 - 309 (2018/08/17)
We report the synthesis and pharmacological evaluation of new 3-aminomethylindoles derivatives with neuroprotective properties designed to present multi-target activity centered on reducing the neuronal Ca2+ overload and preventing phosphatase
COMPOUNDS, COMPOSITIONS AND METHODS
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Figure 15, (2008/06/13)
The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions.