56107-04-1

Basic information

• Product Name: 3-(p-tert-butylphenyl)-2-methylpropanol
• Synonyms: 3-(p-tert-butylphenyl)-2-methylpropanol;4-(1,1-dimethylethyl)-.beta.-methyl-Benzenepropanol;4-(1,1-Dimethylethyl)-β-methylbenzene-1-propanol;3-(4-tert-Butylphenyl)-2-methylpropyl alcohol;Benzenepropanol, 4-(1,1-dimethylethyl)-.beta.-methyl-;Nsc20782
• CAS NO: 56107-04-1
• Molecular Formula: C₁₄H₂₂O
• Molecular Weight: 206.32388
• EINECS: 259-996-2
• Mol File: 56107-04-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 302.4°C at 760 mmHg
• Flash Point: 114.8°C
• Appearance: /
• Density: 0.938g/cm³
• Vapor Pressure: 0.00044mmHg at 25°C
• Refractive Index: 1.502
• PKA: 14.96±0.10(Predicted)
• CAS DataBase Reference: 3-(p-tert-butylphenyl)-2-methylpropanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(p-tert-butylphenyl)-2-methylpropanol(56107-04-1)
• EPA Substance Registry System: 3-(p-tert-butylphenyl)-2-methylpropanol(56107-04-1)

Safety Data

• Hazardous Substances Data: 56107-04-1(Hazardous Substances Data)

Usage

General Description

3-(p-tert-butylphenyl)-2-methylpropanol, also known as Lyral, is a fragrance ingredient commonly found in personal care and household products. It is a colorless liquid with a floral and green scent that is often used to add a fresh and clean aroma to various products. Lyral is a synthetic compound that is known to be a skin allergen for some individuals and is sometimes used as a standard for testing allergenic potential in other compounds. As a result, there have been efforts to reduce and eliminate the use of Lyral in consumer products due to its potential to cause skin sensitization. Despite concerns about its potential to cause skin allergies, it is still found in a wide range of products such as perfumes, lotions, and detergents.

InChI:InChI=1/C14H22O/c1-11(10-15)9-12-5-7-13(8-6-12)14(2,3)4/h5-8,11,15H,9-10H2,1-4H3

Upstream product

• 13586-68-0 p-tert-butyl-α-methyl-3-phenylprop-2-enal 
• 80-54-6 lilial 
• 117721-78-5 (E)-3-(4-(tert-butyl)phenyl)-2-methylprop-2-en-1-ol 
• 507-20-0 tertiary butyl chloride 
• 22436-06-2 2-methyl-3-phenylpropanol 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 63488-10-8 4-tert-butylmagnesium bromide 

Downstream Products

• 160782-65-0 (+/-)-3-[4-(tert-butyl)-2-methylphenyl]-2-methylpropan-1-ol 
• 160782-58-1 (+/-)-3-[4-(tert-butyl)-2-methylphenyl]-2-methylpropanal 
• 212787-40-1 3-(3-tert-butylphenyl)-2-methylpropan-1-ol 
• 22436-06-2 2-methyl-3-phenylpropanol 
• 1292254-18-2 3-(3,5-di-tert-butylphenyl)-2-methylpropanol 

Relevant articles and documents

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Chemoselective hydrogenation of α,β-unsaturated aldehydes with modified Pd/C catalyst

Selective hydrogenation of α,β-unsaturated aldehydes with modified Pd/C catalyst was developed. The reduction of CO bond could be efficiently inhibited by the addition of carbonates, and high selectivity to the corresponding saturated aldehydes was achieved under mild conditions. This protocol provides an alternative for efficient preparation of saturated aldehydes.

Acid promoted CIDT for the deracemization of dihydrocinnamic aldehydes with Betti's base

Racemic α-epimerizable and unfunctionalized aldehydes have been converted into enantiomerically enriched mixtures through a sequence of (i) a conversion into the diastereoisomeric 3-substituted 1-phenyl-2,3-dihydro-1H- naphtho[1,2-e][1,3]oxazines by reaction with the (R)- or (S)-1-(α- aminobenzyl)-2-naphthol (Betti's base), (ii) an acid promoted crystallization-induced diastereoisomer transformation (CIDT), and (iii) a clean cleavage of the dihydro-1,3-naphthoxazinic ring of the enriched diastereoisomer, easily collected by filtration, allowing the recovery of the enantiomerically enriched aldehydes and the chiral auxiliary.