5635-98-3

Basic information

• Product Name: 2-Methoxy-methylphenol
• Synonyms: 2-Methoxy-methylphenol;2-(4-chlorophenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazole-4-carbaldehyde
• CAS NO: 5635-98-3
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.1638
• Mol File: 5635-98-3.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 380.7°C at 760 mmHg
• Flash Point: 184.1°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 5.34E-06mmHg at 25°C
• Refractive Index: 1.666
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.77±0.35(Predicted)
• CAS DataBase Reference: 2-Methoxy-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxy-methylphenol(5635-98-3)
• EPA Substance Registry System: 2-Methoxy-methylphenol(5635-98-3)

Safety Data

• Hazardous Substances Data: 5635-98-3(Hazardous Substances Data)

Usage

General Description

2-Methoxy-methylphenol, also known as guaiacol, is a chemical compound with the molecular formula C7H8O2. It is a clear, oily liquid that is slightly soluble in water and easily soluble in organic solvents. Guaiacol is commonly used as a precursor in the synthesis of various pharmaceuticals, as well as in the production of flavorings and fragrances. It is also used as a disinfectant and as a precursor to various polymers. Guaiacol has a characteristic smoky, spicy odor and is a key component in the flavor profile of smoked foods and certain beverages. In addition, it has been employed as a reagent in various chemical reactions, including as a source of the methoxy functional group. Additionally, guaiacol is utilized in the synthesis of other aromatic compounds and as an intermediate in the manufacture of dyes and resins.

InChI:InChI=1/C11H9ClN2O2/c1-7-10(6-15)11(16)14(13-7)9-4-2-8(12)3-5-9/h2-6,13H,1H3

Upstream product

• 67-56-1 methanol 
• 90-01-7 salicylic alcohol 
• 62723-78-8 2-methoxymethylaniline 
• 10419-28-0 2,2-diphenylchromane 
• 74-88-4 methyl iodide 
• 89-95-2 2-methyl-benzyl alcohol 
• 612-23-7 2-nitrobenzyl chloride 
• 6161-96-2 2-acetoxymethylphenol 
• 19115-31-2 1-(o-hydroxyphenyl)propargylic alcohol 
• 90-05-1 2-methoxy-phenol 
• 126617-98-9 (2-(methoxymethyl)phenyl)boronic acid 
• 60399-02-2 N-methyl-2-hydroxybenzylamine 
• 116585-12-7 2-((tert-butyldimethylsilyl)oxy)benzaldehyde 
• 90-02-8 salicylaldehyde 

Downstream Products

• 27890-67-1 6-methylene-cyclohexa-2,4-dienone 
• 337906-36-2 2-(methoxymethyl)-p-phenylenediamine 
• 1380070-69-8 2-(methoxymethyl)cyclohexa-2,5-diene-1,4-dione oxime 
• 22802-51-3 2-Methoxymethyl-benzochinon-1,4-4-oxim 
• 95-48-7 ortho-cresol 
• 675855-58-0 2-tridecylphenyl trifluoromethanesulfonate 
• 675855-53-5 1-ethoxymethoxy-2-tridecyl-benzene 
• 675855-59-1 2-(2-methylpropyl)phenyl trifluoromethanesulfonate 
• 675855-52-4 1-ethoxymethoxy-2-pentyl-benzene 
• 675855-54-6 1-ethoxymethoxy-2-isobutyl-benzene 
• 96850-25-8 2-tridecylphenol 
• 827-80-5 1-ethoxymethoxy-2-methylbenzene 
• 136-81-2 2-pentylphenol 
• 4167-75-3 2-isobutylphenol 

Relevant articles and documents

Fabricating Bifunctional Co?Al2O3@USY Catalyst via In-Situ Growth Method for Mild Hydrodeoxygenation of Lignin to Naphthenes

To enhance the catalytic activity and stability of metal catalysts in the hydrodeoxygenation of lignin derivatives into naphthenes, a bifunctional Co?Al2O3@USY catalyst was fabricated by the reduction of CoAl layered double hydroxide in-situ grown on the USY zeolite. In the hydrodeoxygenation of guaiacol, a 100.0 % conversion with cyclohexane yield up to 93.6 % was achieved at 180 °C, 3 MPa for 4 h, which should be the hitherto lowest reaction temperature that has been reported over Co-based metal catalysts. This catalyst was also relatively stable with 5 runs and exhibited excellent catalytic performance in the hydrodeoxygenation of other lignin model compounds and even real lignin feedstock into naphthenes. The high-efficiency of Co?Al2O3@USY was attributed to the synergistic effect between well-dispersed small Co nanoparticles and abundant acidic sites on the USY surface, while the outstanding stability was attributed to the anchoring effect of Al2O3 matrix to Co nanoparticles which avoided the leaching of Co species and particle agglomeration. This work provides a potential strategy for the design of an efficient and stable catalyst for lignin utilization.

A naphthoquine phosphate process impurity and its synthesis method

The invention discloses a compound of formula (I) reported shown naphthoquine phosphate has not seen the structure of process impurities, and provides a alkyl aminomethyl phenol is converted into the corresponding alkyl ethoxy methyl phenol, or substitute

Copper(I)-catalyzed hydroalkoxylation/hydrogen-bonding-induced asymmetric hetero-diels-alder cycloaddition cascade: An approach to aromatic spiroketals

One thing leads to another: Bis(benzannelated) 5,6-spiroketal skeletons can be constructed by an efficient cascade process involving an unprecedented CuI-catalyzed intramolecular alkyne hydroalkoxylation and an asymmetric hetero-Diels-Alder cyc