56409-82-6

Basic information

• Product Name: 2,3-diphenyl-4(1H)-quinolinone
• Synonyms: 2,3-diphenyl-4(1H)-quinolinone
• CAS NO: 56409-82-6
• Molecular Formula: C₂₁H₁₅NO
• Molecular Weight: 297.3499
• Mol File: 56409-82-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-diphenyl-4(1H)-quinolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diphenyl-4(1H)-quinolinone(56409-82-6)
• EPA Substance Registry System: 2,3-diphenyl-4(1H)-quinolinone(56409-82-6)

Safety Data

• Hazardous Substances Data: 56409-82-6(Hazardous Substances Data)

Upstream product

• 60227-50-1 1,4,5-triphenyl-2,3-dihydropyrrole-2,3-dione 
• 1256842-46-2 ethyl 3-cyano-2,3-diphenyl-3-phenylaminopropanoate 
• 100-44-7 benzyl chloride 
• 89-95-2 2-methyl-benzyl alcohol 
• 835-38-1 1-(2-aminophenyl)-2-phenylethanone 
• 100-51-6 benzyl alcohol 
• 488825-21-4 2,3-diphenyl-2,3-dihydroquinolin-4(1H)-one 
• 108-88-3 toluene 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 16714-27-5 (2-azidophenyl)(phenyl)methanone 
• 1885-29-6 anthranilic acid nitrile 
• 1148108-54-6 4-methoxy-2,3-diphenylquinoline 
• 2556-46-9 N,N'-diphenylbenzamidine 
• 83-13-6 diethyl 2-phenylmalonate 

Relevant articles and documents

One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene

Herein, we describe the iron(III)-catalyzed oxidative coupling of alcohol/methyl arene with 2-amino phenyl ketone to synthesize 4-quinolone. Alcohols and methyl arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-butyl peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates.

Microwave-assisted synthesis of polysubstituted 4-quinolones from deprotonated α-aminonitriles

The α-alkylation of deprotonated N-aryl-α-aminonitriles with α-bromoesters furnishes intermediates that can be cyclized to 4-quinolones upon microwave irradiation. Alternatively, base-induced dehydrocyanation of the alkylation products furnishes enaminoes

2-aryl-4-chloro-3-iodoquinolines as substrates for the synthesis of 2,3-diaryl-4-methoxyquinolines

Sequential functionalisation of 2-aryl-4-chloro-3-iodoquinolines via palladium-catalysed cross-coupling with phenylboronic acid followed by displacement of the 4-chloro atom from the resulting 2,3-diaryl-4- chloroquinolines with methoxide ion yielded 2,3-