569332-20-3

Basic information

• Product Name: Benzene, 1-(1,1-dimethyloctyl)-3,5-dimethoxy-
• CAS NO: 569332-20-3
• Molecular Formula: C18H30O2
• Molecular Weight: 278.435
• Mol File: 569332-20-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1,1-dimethyloctyl)-3,5-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1,1-dimethyloctyl)-3,5-dimethoxy-(569332-20-3)
• EPA Substance Registry System: Benzene, 1-(1,1-dimethyloctyl)-3,5-dimethoxy-(569332-20-3)

Safety Data

• Hazardous Substances Data: 569332-20-3(Hazardous Substances Data)

Upstream product

• 569332-22-5 2-methyl-2-(4-hydroxy-3,5-dimethoxyphenyl)nonane 
• 821-55-6 2-Nonanone 
• 10297-57-1 2-methylnonan-2-ol 

Downstream Products

• 1399049-48-9 C₁₈H₂₈O₃ 
• 1399049-81-0 7-(1,1-dimethyloctyl)-5-hydroxy-3-(2-hydroxybenzyl)-2H-chromen-2-one 
• 1399049-65-0 C₂₈H₃₆O₄ 

Relevant articles and documents

Structure-activity relationships for 1′,1′-dimethylalkyl-Δ8-tetrahydrocannabinols

A series of 1′,1′-dimethylalkyl-Δ8-tetrahydrocannabinol analogues with C-3 side chains of 2-12 carbon atoms has been synthesized and their in vitro and in vivo pharmacology has been evaluated. The lowest member of the series, 1′,1′-dimethylethyl-Δ8-THC (8, n=0) has good affinity for the CB1 receptor, but is inactive in vivo. The dimethylpropyl (8, n=1) through dimethyldecyl (8, n=8) all have high affinity for the CB1 receptor and are full agonists in vivo. 1′,1′-Dimethylundecyl-Δ8-THC (8, n=9) has significant affinity for the receptor (Ki=25.8±5.8 nM), but has reduced potency in vivo. The dodecyl analogue (8, n=10) has little affinity for the CB1 receptor and is inactive in vivo. A quantitative structure-activity relationship study of the side chain region of these compounds is consistent with the concept that for optimum affinity and potency the side chain must be of a length which will permit its terminus to loop back in proximity to the phenolic ring of the cannabinoid.