57023-37-7

Basic information

• Product Name: 3-[(2-phenylhydrazinylidene)methyl]pyridine
• CAS NO: 57023-37-7
• Molecular Formula: C₁₂H₁₁N₃
• Molecular Weight: 197.2358
• Mol File: 57023-37-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 351.6°C at 760 mmHg
• Flash Point: 166.5°C
• Density: 1.07g/cm³
• Vapor Pressure: 4.06E-05mmHg at 25°C
• Refractive Index: 1.592
• CAS DataBase Reference: 3-[(2-phenylhydrazinylidene)methyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2-phenylhydrazinylidene)methyl]pyridine(57023-37-7)
• EPA Substance Registry System: 3-[(2-phenylhydrazinylidene)methyl]pyridine(57023-37-7)

Safety Data

• Hazardous Substances Data: 57023-37-7(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 3731-52-0 3-Aminomethylpyridine 
• 865-47-4 potassium tert-butylate 
• 78-84-2 isobutyraldehyde 
• 500-22-1 3-pyridinecarboxaldehyde 

Downstream Products

• 109722-08-9 1-(2,6-dichloro-benzyl)-3-(phenylhydrazono-methyl)-pyridinium; bromide 
• 109810-10-8 1-(2,6-dichloro-benzyl)-1,4-dihydro-pyridine-3-carbaldehyde-phenylhydrazone 
• 16518-17-5 potassium nicotinate 
• 27268-04-8 (E)-3-(1-phenylpyrazol-4-yl)prop-2-enoic acid 
• 75594-89-7 1-phenyl-4-(3-methyliminopropenyl)pyrazole 
• 2600-63-7 3-(1-phenylpyrazol-4-yl)acrylaldehyde 
• 1134-50-5 4-carboxy-1-phenylpyrazole 
• 54605-72-0 1-phenyl-1H-pyrazole-4-carbaldehyde 
• 100-54-9 pyridine-3-carbonitrile 
• 7684-30-2 N,N-dimethyl-N'-phenylcarbamimidic chloride 
• 60441-21-6 1-Methyl-3-(phenyl-hydrazonomethyl)-pyridinium; iodide 

Relevant articles and documents

Kinetics and Mechanism for Pyridinecarboxaldehyde Phenylhydrazone Formation

Phenylhydrazone formation from 4- and 3-pyridinecarboxaldehyde occurs with rate-determining carbinolamine dehydration under acidic, neutral, and basic conditions.Plots of first-order rate constants against amine concentration are nonlinear for these subst

A class of highly effective broad-spectrum plant antimicrobial agentS

The present invention relates to a class of benzohydrazone compounds and synthetic methods thereof and drugs containing the compound thereof and applications thereof. The hydrate compounds involved in the present invention have the advantages of simple structure, easy synthesis, strong antibacterial activity, wide antibacterial spectrum, small toxicity to animals and plants and low composition, and can be used as active ingredients or synergistic ingredients for the development of new high-efficiency broad-spectrum plant antibacterial agents.

Exceptionally rapid oxime and hydrazone formation promoted by catalytic amine buffers with low toxicity

Hydrazone and oxime bond formation between α-nucleophiles (e.g. hydrazines, alkoxy-amines) and carbonyl compounds (aldehydes and ketones) is convenient and is widely applied in multiple fields of research. While the reactants are simple, a substantial drawback is the relatively slow reaction at neutral pH. Here we describe a novel molecular strategy for accelerating these reactions, using bifunctional buffer compounds that not only control pH but also catalyze the reaction. The buffers can be employed at pH 5-9 (5-50 mM) and accelerate reactions by several orders of magnitude, yielding second-order rate constants of >10 M-1 s-1. Effective bifunctional amines include 2-(aminomethyl)imidazoles and N,N-dimethylethylenediamine. Unlike previous diaminobenzene catalysts, the new buffer amines are found to have low toxicity to human cells, and can be used to promote reactions in cellular applications.