57027-74-4 Usage
Description
1-Amino-1-deoxy-D-mannitol, also known as 1-deoxy-1-amino-D-glucitol, is a chemical compound that belongs to the family of aminosugars. It is a derivative of mannitol and is primarily used in the production of various pharmaceuticals and drugs. 1-Amino-1-deoxy-D-mannitol has been studied for its potential therapeutic effects, particularly in the treatment of diabetes and neurodegenerative disorders. Additionally, 1-Amino-1-deoxy-D-mannitol has also been shown to possess antioxidant and anti-inflammatory properties, making it a potential candidate for the development of novel therapeutic agents for various medical conditions. Overall, this chemical compound holds promise for the development of new drugs and treatment options in the field of medicine.
Uses
Used in Pharmaceutical Industry:
1-Amino-1-deoxy-D-mannitol is used as an intermediate in the synthesis of various pharmaceuticals and drugs for its potential therapeutic effects.
Used in Diabetes Treatment:
1-Amino-1-deoxy-D-mannitol is used as a therapeutic agent for the treatment of diabetes, potentially improving glycemic control and insulin sensitivity.
Used in Neurodegenerative Disorders Treatment:
1-Amino-1-deoxy-D-mannitol is used as a therapeutic agent for the treatment of neurodegenerative disorders, potentially slowing down the progression of these conditions.
Used in Antioxidant and Anti-Inflammatory Applications:
1-Amino-1-deoxy-D-mannitol is used as an antioxidant and anti-inflammatory agent, potentially reducing oxidative stress and inflammation in various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 57027-74-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,0,2 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 57027-74:
(7*5)+(6*7)+(5*0)+(4*2)+(3*7)+(2*7)+(1*4)=124
124 % 10 = 4
So 57027-74-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4-,5-,6-/m1/s1
57027-74-4Relevant articles and documents
Synthesis and Hydrolytic Lability of α-Phenoxyacetamides Containing Hydroxy Groups in the N-alkyl Residue
Anelli, Pier Lucio,Brocchetta, Marino,Canipari, Sonia,Losi, Pietro,Manfredi, Giuseppe,et al.
, p. 135 - 142 (2007/10/03)
Secondary and tertiary amides of 3,5-biscarbonyl>phenoxyacetic acid bearing hydroxy groups in positions β (β-OH) and γ (γ-OH) relative to the acetamide nitrogen atom have been synthesized.Such amides easily undergo cleavage of the acetamide bond in water at neutral pH.Hydrolysis rate constant for a series of such amides and protonation constants for the corresponding leaving amines were determined.No simple correlation between the two parameters could be found.A study of the dependence of these parameters on the structural features of the substrates, such as the presence of an N-methyl group and number of β-OH and γ-OH groups, was carried out.All these features lead to enhancement of the amide hydrolysis rate and a synergistic effect is operative when both N-methyl and β-OH groups are contained in the substrate.Presence of a methyl group increases the basicity of amines whereas β-OH and γ-OH groups have the opposite effect.Mechanistic speculations seem to indicate that the abnormal lability of the acetamide bond is due to protic-like catalysis by an intramolecular OH...N hydrogen bond.