57238-67-2Relevant articles and documents
Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C-H Amination
Hu, Yang,Lang, Kai,Li, Chaoqun,Gill, Joseph B.,Kim, Isaac,Lu, Hongjian,Fields, Kimberly B.,Marshall, McKenzie,Cheng, Qigan,Cui, Xin,Wojtas, Lukasz,Zhang, X. Peter
supporting information, p. 18160 - 18169 (2019/11/19)
Both arylsulfonyl and alkylsulfonyl azides can be effectively activated by the cobalt(II) complexes of D2-symmetric chiral amidoporphyrins for enantioselective radical 1,5-C-H amination to stereoselectively construct 5-membered cyclic sulfonami
Nickel-catalyzed allylic substitution of simple alkenes
Matsubara, Ryosuke,Jamison, Timothy F.
supporting information; experimental part, p. 6880 - 6881 (2010/07/05)
Nickel-catalyzed intermolecular allylic substitution of simple alkenes (ethylene and alpha olefins) is described. This method is the first catalytic intermolecular process for direct allylation of nonconjugated, nonstrained simple alkenes. Catalyst loadings as low as 2.5 mol % Ni afford the desired product in high yield in both gram-scale and smaller scale coupling reactions.
A general model for selectivity in olefin cross metathesis
Chatterjee, Arnab K.,Choi, Tae-Lim,Sanders, Daniel P.,Grubbs, Robert H.
, p. 11360 - 11370 (2007/10/03)
In recent years, olefin cross metathesis (CM) has emerged as a powerful and convenient synthetic technique in organic chemistry; however, as a general synthetic method, CM has been limited by the lack of predictability in product selectivity and stereoselectivity. Investigations into olefin cross metathesis with several classes of olefins, including substituted and functionalized styrenes, secondary allylic alcohols, tertiary allylic alcohols, and olefins with α-quaternary centers, have led to a general model useful for the prediction of product selectivity and stereoselectivity in cross metathesis. As a general ranking of olefin reactivity in CM, olefins can be categorized by their relative abilities to undergo homodimerization via cross metathesis and the susceptibility of their homodimers toward secondary metathesis reactions. When an olefin of high reactivity is reacted with an olefin of lower reactivity (sterically bulky, electron-deficient, etc.), selective cross metathesis can be achieved using feedstock stoichiometries as low as 1:1. By employing a metathesis catalyst with the appropriate activity, selective cross metathesis reactions can be achieved with a wide variety of electron-rich, electron-deficient, and sterically bulky olefins. Application of this model has allowed for the prediction and development of selective cross metathesis reactions, culminating in unprecedented three-component intermolecular cross metathesis reactions.
