57356-77-1

Basic information

• Product Name: 4-acetoxy-3-methyl-2-cyclohexen-1-one
• Synonyms: 4-acetoxy-3-methyl-2-cyclohexen-1-one
• CAS NO: 57356-77-1
• Molecular Weight: 168.192
• Mol File: 57356-77-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-acetoxy-3-methyl-2-cyclohexen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetoxy-3-methyl-2-cyclohexen-1-one(57356-77-1)
• EPA Substance Registry System: 4-acetoxy-3-methyl-2-cyclohexen-1-one(57356-77-1)

Safety Data

• Hazardous Substances Data: 57356-77-1(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 57356-79-3 4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 184481-10-5 1-methyl-7-oxabicyclo<4.1.0>heptan-3-one 
• 31883-98-4 3-methylcyclohex-3-en-1-one 
• 13697-84-2 1-methoxy-5-methyl-cyclohexa-1,4-diene 

Downstream Products

• 130660-22-9 Acetic acid (1S,2R)-2-methyl-4-oxo-cyclohexyl ester 
• 184653-97-2 (R)-4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 136658-05-4 (S)-4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 136658-04-3 (-)-4-acetoxy-3-methyl-2-cyclohexen-1-one 
• 184481-14-9 (3S,3aS,4R,7S,7aS)-7-(tert-Butyl-diphenyl-silanyloxy)-4,7a-dimethyl-3-(2-methyl-allyl)-octahydro-inden-4-ol 
• 184481-09-2 (7S,7aS)-7-(tert-Butyl-diphenyl-silanyloxy)-7a-methyl-1,2,5,6,7,7a-hexahydro-inden-4-one 
• 184481-17-2 (3S,3aS,4R,7S,7aS)-7-(tert-Butyl-diphenyl-silanyloxy)-4,7a-dimethyl-3-(2-methyl-propenyl)-octahydro-inden-4-ol 
• 184481-12-7 (3S,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-3-(2-[1,3]dioxan-2-yl-ethyl)-3-methyl-cyclohexanone 
• 184481-15-0 (3S,3aS,7S,7aS)-7-(tert-Butyl-diphenyl-silanyloxy)-7a-methyl-3-(2-methyl-propenyl)-octahydro-inden-4-one 
• 184481-13-8 (3S,3aR,7S,7aS)-7-(tert-Butyl-diphenyl-silanyloxy)-7a-methyl-3-(2-methyl-allyl)-octahydro-inden-4-one 
• 136611-27-3 4-<(benzyl)oxy>-3-methyl-2-cyclohexenone 
• 136611-25-1 (S)-4-<(t-butyldimethylsilyl)oxy>-3-methyl-2-cyclohexenone 
• 57356-80-6 (4S)-3-methyl-4-<(tetrahydropyranyl)oxy>-2-cyclohexenone 
• 136611-30-8 (3S,4S)-4-<(t-butyldimethylsilyl)oxy>-3-methyl-3-vinylcyclohexanone 

Relevant articles and documents

A concise, stereocontrolled total synthesis of rippertenol

The first total synthesis of the unique terpene rippertenol, a molecule with dense stereochemical complexity arrayed on a compact framework largely devoid of functional groups, is described. Key elements include orchestrated and unique applications of aldol condensations, Diels-Alder chemistry, and a ring expansion to advance a chiral starting material containing a single chiral center into the final target in a concise and diastereocontrolled manner.

Synthesis of optically active cyclohexenol derivatives via enzyme catalyzed ester hydrolysis of 4-acetoxy-3-methyl-2-cyclohexenone

The optically active cyclohexenol derivatives 9a-9d, and 10a-10c are synthesized from (-)-6, which is obtained by enzymatic ester hydrolysis of racemic 8. Attempts towards the synthesis of the taxane skeleton are described.