57477-93-7

Basic information

• Product Name: Benzaldehyde, 4-bromo-, hydrazone
• Synonyms: hydrazone of p-bromobenzaldehyde;Benzaldehyde,4-bromo-,hydrazone;4-bromobenzaldehyde hydrazone
• CAS NO: 57477-93-7
• Molecular Formula: C7H7BrN2
• Molecular Weight: 199.05
• Mol File: 57477-93-7.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 285.8±42.0 °C(Predicted)
• Density: 1.52±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzaldehyde, 4-bromo-, hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-bromo-, hydrazone(57477-93-7)
• EPA Substance Registry System: Benzaldehyde, 4-bromo-, hydrazone(57477-93-7)

Safety Data

• Hazardous Substances Data: 57477-93-7(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 24523-45-3 bis-(4-bromo-benzylidene)-hydrazine 
• 136350-66-8 1-bromo-4-(2,2-dibromovinyl)benzene 
• 115665-68-4 (E)-1-bromo-4-(2-bromovinyl)benzene 
• 115665-77-5 (Z)-1-[2-bromovinyl]-4-bromobenzene 
• 98453-57-7 4-(4-bromophenyl)butanoic acid methyl ester 
• 155820-88-5 1-bromo-4-(2,2,2-trifluoroethyl)benzene 
• 51991-28-7 1-bromo-4-neopentylbenzene 
• 2051-99-2 1-bromo-4-isobutylbenzene 

Relevant articles and documents

Zinc(II) Complexes of N,N-Di(2-picolyl)hydrazones

We report on N,N-di(2-picolyl)hydrazone (DPH) ligands that are capable of binding metal ions in two isomeric forms depending on the nature of the hydrazone substituent. When the hydrazone substituent is not coordinating, the metal ion prefers the N,N-di(2-picolyl)amino (DPA) site, which is a known tridentate ligand that anchors on the sp3-hybridized amino nitrogen atom. When the hydrazone substituent is coordinating, the metal ion instead anchors on the sp2-hybridized imino nitrogen atom to afford a different structural isomer. Zinc(II) is used as a representative transition-metal ion for characterizing the coordination chemistry of DPH in both solution and solid states.

Submonomer synthesis of peptoids containingtrans-inducingN-imino- andN-alkylamino-glycines

The use of hydrazones as a new type of submonomer in peptoid synthesis is described, giving access to peptoid monomers that are structure-inducing. A wide range of hydrazones were found to readily react with α-bromoamides in routine solid phase peptoid submonomer synthesis. Conditions to promote a one-pot cleavage of the peptoid from the resin and reduction to the correspondingN-alkylamino side chains were also identified, and both theN-imino- andN-alkylamino glycine residues were found to favor thetrans-amide bond geometry by NMR, X-ray crystallography, and computational analyses.

Reduction over Condensation of Carbonyl Compounds through a Transient Hemiaminal Intermediate Using Hydrazine

Reduction of carbonyl moieties to the corresponding alcohol using simply hydrazine hydrate has been considerably unfeasible until now due to the well-known condensation reaction. However, herein, we report that using an excess of 20-fold equivalents, the reduction proceeds in excellent yields. 1H NMR study of the reaction and density functional theory (DFT) calculations indicate that the final fate of the hemiaminal intermediate is crucial to obtain the alcohol or the hydrazone.