57641-44-8

Basic information

• Product Name: 3-Pentanone, 1,5-bis(4-methylphenyl)-
• CAS NO: 57641-44-8
• Molecular Formula: C19H22O
• Molecular Weight: 266.37700
• Mol File: 57641-44-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-Pentanone, 1,5-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentanone, 1,5-bis(4-methylphenyl)-(57641-44-8)
• EPA Substance Registry System: 3-Pentanone, 1,5-bis(4-methylphenyl)-(57641-44-8)

Safety Data

• Hazardous Substances Data: 57641-44-8(Hazardous Substances Data)

Upstream product

• 39777-55-4 bis(4-methylstyryl)ketone 
• 104-87-0 4-methyl-benzaldehyde 
• 100-46-9 benzylamine 

Downstream Products

• 199990-09-5 4-(5-Ethyl-1-methyl-4-{3-[4-p-tolyl-2-(2-p-tolyl-ethyl)-butylamino]-benzoyl}-1H-pyrrol-2-yl)-butyric acid ethyl ester 

Relevant articles and documents

Antimicrobial Activity of Monoketone Curcuminoids Against Cariogenic Bacteria

We evaluated the antimicrobial activity of 25 monoketone curcuminoids (MKCs) against a representative panel of cariogenic bacteria in terms of their minimum inhibitory concentration (MIC) values. Curcumin A (10) displayed promising activity against Streptococcus mutans (MIC?=?50?μg/ml) and Streptococcus mitis (MIC?=?50?μg/ml) as well as moderate activity against S.?sanguinis (MIC?=?100?μg/ml), Lactobacillus casei (MIC?=?100?μg/ml), and Streptococcus salivarius (MIC?=?200?μg/ml). Results indicated higher activity of compound 10 than that of its bis-β-diketone analog. Additionally, compounds 3a (1,5-bis(4-methylphenyl)pentan-3-one) and 7b (1,5-bis(4-bromophenyl)pentan-3-ol) were moderately active against S.?mitis (MIC?=?100?μg/ml) and S.?salivarus (MIC?=?200?μg/ml).

Diphenyl derivatives of polyamine compounds having a piperidine moiety

Novel diphenyl and loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity, and as such are advantageously included as the active agent in surgical scrubs, antibacterial soaps, as preservatives in cosmetic preparations, and the like. They also can be used for topical treatment of dermatological conditions having a bacterial origin or implication such as Acne vulgaris.

Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines

A composition comprising tris-(hydroxymethyl)aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines, their acid addition salts, and mixtures thereof are useful as antibacterial agents. The composition is particularly useful because of the synergistic improvement obtained against strains of the genus Pseudomonas, as well as other genera.