577705-94-3

Basic information

• Product Name: Carbamic acid, [4-iodo-1-(phenylmethoxy)-3-isoquinolinyl]-, 1,1-dimethylethyl ester
• CAS NO: 577705-94-3
• Molecular Formula: C21H21IN2O3
• Molecular Weight: 476.314
• Mol File: 577705-94-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [4-iodo-1-(phenylmethoxy)-3-isoquinolinyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [4-iodo-1-(phenylmethoxy)-3-isoquinolinyl]-, 1,1-dimethylethyl ester(577705-94-3)
• EPA Substance Registry System: Carbamic acid, [4-iodo-1-(phenylmethoxy)-3-isoquinolinyl]-, 1,1-dimethylethyl ester(577705-94-3)

Safety Data

• Hazardous Substances Data: 577705-94-3(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 13130-79-5 3-amino-1-bromoisoquinoline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 577705-93-2 1-benzyloxy-3-[(tert-butyloxycarbonyl)amino]isoquinoline 
• 577705-92-1 3-amino-1-benzyloxyisoquinoline 
• 20194-18-7 sodium phenyl-methanolate 

Downstream Products

• 577705-96-5 5-benzyloxy-3-N-(tert-butyloxycarbonyl)-1-(chloromethyl)-1,2-dihydropyrrolo[2,3-c]isoquinoline 
• 577705-97-6 (S)-5-benzyloxy-3-N-(tert-butyloxycarbonyl)-1-(chloromethyl)-1,2-dihydropyrrolo[2,3-c]isoquinoline 
• 577705-98-7 (R)-5-benzyloxy-3-N-(tert-butyloxycarbonyl)-1-(chloromethyl)-1,2-dihydropyrrolo[2,3-c]isoquinoline 
• 577705-95-4 3-[N-(tert-butyloxycarbonyl)-N-(3-chloroprop-2-en-1-yl)amino]-1-benzyloxy-4-iodoisoquinoline 

Relevant articles and documents

Synthesis and Evaluation of Duocarmycin and CC-1065 Analogues Incorporating the 1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]-3-azaindol-4-one (CBA) Alkylation Subunit

An efficient eight-step synthesis (53% overall) and the evaluation of 1,2,9,9a-tetrahydrocyclopropa-[c]benz[e]-3-azaindol-4-one (CBA) and its derivatives containing an aza variant of the CC-1065/ duocarmycin alkylation subunit are detailed. This unique de