57825-30-6

Basic information

• Product Name: 1-(bromomethyl)-4-ethylbenzene
• Synonyms: 1-(bromomethyl)-4-ethylbenzene;4-ethylbenzyl bromide（WS204981）
• CAS NO: 57825-30-6
• Molecular Formula: C₉H₁₁Br
• Molecular Weight: 199.09
• Mol File: 57825-30-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 14.5-15.2 °C
• Boiling Point: 84 °C
• Appearance: /
• Density: 1.312±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-(bromomethyl)-4-ethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(bromomethyl)-4-ethylbenzene(57825-30-6)
• EPA Substance Registry System: 1-(bromomethyl)-4-ethylbenzene(57825-30-6)

Safety Data

• Hazardous Substances Data: 57825-30-6(Hazardous Substances Data)

Usage

Description

1-(bromomethyl)-4-ethylbenzene is a chemical compound with the formula C9H11Br. It is a derivative of benzene, featuring a bromomethyl group and an ethyl group attached to the benzene ring. The bromine atom endows this compound with high reactivity, making it a versatile intermediate in the synthesis of various organic compounds.

Uses

Used in Pharmaceutical Industry:
1-(bromomethyl)-4-ethylbenzene is used as a synthetic intermediate for the development of pharmaceuticals. Its reactivity allows for the creation of new molecules with potential medicinal properties, contributing to the advancement of drug discovery and design.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(bromomethyl)-4-ethylbenzene is utilized as a precursor in the synthesis of agrochemicals. Its structural features facilitate the production of compounds that can be used in the development of pesticides, herbicides, and other agricultural chemicals to enhance crop protection and yield.
Used in Dye Industry:
1-(bromomethyl)-4-ethylbenzene is employed as a building block in the dye industry. Its chemical properties enable the synthesis of novel dyes with diverse color characteristics and applications, such as in textiles, printing, and other industrial processes.
Used in Organic Chemistry Research:
1-(bromomethyl)-4-ethylbenzene is also used as a research tool in organic chemistry. Its reactivity and structural attributes make it valuable for studying reaction mechanisms, exploring new synthetic routes, and understanding the properties of related compounds in academic and industrial research settings.

Upstream product

• 1467-05-6 4-ethylbenzylchloride 
• 50-00-0 formaldehyd 
• 100-41-4 ethylbenzene 
• 10035-10-6 hydrogen bromide 
• 619-64-7 p-ethylbenzoic acid 
• 768-59-2 4-ethylbenzyl alcohol 
• 40391-19-3 (1R*,1'RS*)-1-cyclohex-2-enylethanol 
• 16331-45-6 p-ethylbenzoyl chloride 
• 4748-78-1 4-ethylbenzylaldehyde 

Downstream Products

• 1026438-70-9 2-(4-Ethyl-benzyl)-4,4,4-trifluoro-3-oxo-butyric acid ethyl ester 
• 622-96-8 4-methylethylbenzene 
• 5089-31-6 tris(trimethylsilyl)silyl bromide 
• 108-88-3 toluene 
• 244088-47-9 7-O-p-ethylbenzyl-25-O-methyl-26-O-t-butyldimethylsilylmonensin methyl ester 
• 143251-68-7 2-acetylamino-2-(4-ethylbenzyl)malonic acid diethyl ester 
• 492446-76-1 1-[1-(4-Bromomethyl-phenyl)-ethoxy]-2,2,6,6-tetramethyl-piperidine 
• 4313-77-3 D,L-p-ethylphenylalanine 
• 193357-73-2 4-(4-ethylbenzyl)piperidine hydrochloride 
• 142654-07-7 [2-chloro-1-(4-ethylbenzyloxy)-5-phenoxy]benzene 
• 1004780-04-4 (3'R,4'S,5'R,6'R,7S)-3',4',5'-tris-benzyloxy-6'-benzyloxymethyl-1-[(4-ethylphenyl)methyl]-3',4',5',6'-tetrahydro-spiro[furo[3,4-f]indole-7(5H),2'-[2H]pyran] 
• 1155361-11-7 1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-[N-allyl-N-(4-ethylbenzyl)-amino]-2-propanol 
• 660842-01-3 1,3-dimethoxy-2-(4-ethylbenzyl)benzene 
• 1427308-25-5 tert-butyl 2,2-dimethyl-5-(4-(4-ethylbenzyl)phenethyl)-1,3-dioxan-5-ylcarbamate 

Relevant articles and documents

Tandem catalytic C(sp3)-H amination/sila-sonogashira-hagihara coupling reactions with iodine reagents

A new tandem C-N and C-C bond-forming reaction has been achieved through RhII/Pd0 catalysis. The sequence first involves an iodine(III) oxidant, then the in situ generated iodine(I) by-product is used as a coupling partner. The overall process demonstrates the synthetic value of iodoarenes produced in trivalent iodine reagent mediated oxidations. I(003) is a double agent: A tandem C-N and C-C bond-forming reaction has been achieved through RhII/Pd0 catalysis. The sequence first involves an iodine(III) oxidant, then the in situ generated iodine(I) by-product is used as a coupling partner. The overall process affords complex building blocks with high yields, and demonstrates the synthetic value of iodoarenes produced in trivalent iodine reagent mediated oxidations.

Process for Producing Aromatic Aldehyde Compound

A process for producing an aromatic aldehyde compound has steps of converting alkyl-substituted or non-substituted benzene into a compound of formula I by halomethylation, and allowing the compound of formula I and alkyl aldehyde to react in presence of phase transfer catalyst at a reaction temperature under alkaline condition to obtain the aromatic aldehyde compound.

Making a difference on excited-state chemistry by controlling free space within a nanocapsule: Photochemistry of 1-(4-alkylphenyl)-3-phenylpropan-2-ones

The free space within a reaction cavity plays a determining role during the excited-state reaction of 1-(4-alkylphenyl)-3-phenylpropan-2-ones included within a capsule formed by two molecules of a deep cavity cavitand. By controlling the free space within the reaction cavity through remote alkyl substitution on the reactant ketone it is possible to control the yield of the rearrangement product shown above.