57918-64-6

Basic information

• Product Name: 1-(2-bromophenyl)-2-phenylethane
• Synonyms: 1-(2-bromophenyl)-2-phenylethane
• CAS NO: 57918-64-6
• Molecular Weight: 261.161
• Mol File: 57918-64-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-(2-bromophenyl)-2-phenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-bromophenyl)-2-phenylethane(57918-64-6)
• EPA Substance Registry System: 1-(2-bromophenyl)-2-phenylethane(57918-64-6)

Safety Data

• Hazardous Substances Data: 57918-64-6(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 6630-33-7 ortho-bromobenzaldehyde 
• 100-52-7 benzaldehyde 
• 36901-75-4 (2-bromobenzyl)triphenylphosphonium bromide 
• 536-74-3 phenylacetylene 
• 21375-88-2 1-bromo-2-(phenylethenyl)benzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 109-72-8 n-butyllithium 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 78602-28-5 1-bromo-2-(2-phenylethenyl)benzene 
• 59485-34-6 1,2-bis(2-bromophenyl)ethane 
• 78602-27-4 1-(o-bromophenyl)-2-phenylethanol 

Downstream Products

• 776-35-2 9,10-dihydrophenanthrene 
• 1309368-08-8 (+)-3,4-dihydro-3-phenyl-2H-1λ⁶-benzo[e][1,2]thiazine 1,1-dioxide 
• 1351416-42-6 C₁₄H₁₃N₃O₂S 
• 206262-26-2 C₁₄H₁₃ClO₂S 
• 2732-90-3 5-methylene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene 
• 50-48-6 amitryptyline 
• 72-69-5 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine 
• 1438824-78-2 2-phenylethylphenyl dimethylsilane 

Relevant articles and documents

Catalytic Asymmetric Synthesis of Atropisomeric Quinolines through the Friedl?nder Reaction

A phosphoric acid catalyzed atroposelective Friedl?nder reaction was developed in which acetylacetone and a variety of 2′-substituted 2-Aminobenzophenones were successfully employed to give optically active biaryl quinolines in good yields and with high enantioselectivities.

Construction of dibenzo-fused seven- to nine-membered carbocycles via Bronsted acid-promoted intramolecular Friedel - Crafts-type alkenylation

Bronsted acid-promoted intramolecular hydroarylation of alkynylbenzenes carrying an arylalkyl group at the ortho-position leads to alkylidenedibenzo[a,d]cycloheptenes, -octenes and -nonenes in up to quantitative yield with complete regioselectivity. The scope and limitation of this reaction and application to the synthesis of tricyclic antidepressants are described.

Iridium-catalyzed borylation of secondary benzylic C-H bonds directed by a hydrosilane

Most functionalizations of C-H bonds by main-group reagents occur at aryl or methyl groups. We describe a highly regioselective borylation of secondary benzylic C-H bonds catalyzed by an iridium precursor and 3,4,7,8-tetramethyl-1, 10-phenanthroline as the ligand. The reaction is directed to the benzylic position by a hydrosilyl substituent. This hydrosilyl directing group is readily deprotected or transformed to other functional groups after the borylation reaction, providing access to a diverse set of secondary benzylboronate esters by C-H borylation chemistry.