58416-32-3

Basic information

• Product Name: 5-chloro-6-nitroquinoline
• CAS NO: 58416-32-3
• Molecular Formula: C₉H₅ClN₂O₂
• Molecular Weight: 208.6012
• Mol File: 58416-32-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 368.6°C at 760 mmHg
• Flash Point: 176.7°C
• Density: 1.484g/cm³
• Vapor Pressure: 2.68E-05mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: 5-chloro-6-nitroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-6-nitroquinoline(58416-32-3)
• EPA Substance Registry System: 5-chloro-6-nitroquinoline(58416-32-3)

Safety Data

• Hazardous Substances Data: 58416-32-3(Hazardous Substances Data)

Upstream product

• 108-42-9 3-chloro-aniline 
• 712-33-4 3-chloro-4-nitroacetanilide 
• 56-81-5 glycerol 
• 588-07-8 3-Chloroacetanilide 
• 825-41-2 3-chloro-4-nitroaniline 

Relevant articles and documents

Synthesis of mono-substituted derivatives of 6-aminoquinoline

Several 6-aminoquinoline derivatives, which could be used in drug design, have been synthesized. The reaction conditions were comparatively studied, and the p-chloroaniline was used as optimum oxidant in Skraup-Doebner-Von Miller reaction. The nitro group was reduced effectively by SnCl2 with no halo-removed occurred.