5857-42-1

Basic information

• Product Name: p-Methoxybenzenesulfonic acid
• Synonyms: p-Methoxybenzenesulfonic acid;4-Methoxybenzensulfonic acid, 95%;4-methoxylbenzenesulfonic acid
• CAS NO: 5857-42-1
• Molecular Formula: C₇H₈O₄S
• Molecular Weight: 188.2
• Mol File: 5857-42-1.mol
• Article Data: 39

Chemical Properties

• Melting Point: 86-88℃
• Appearance: White to pink/Crystalline Powder or Solid
• Density: 1.381
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: p-Methoxybenzenesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: p-Methoxybenzenesulfonic acid(5857-42-1)
• EPA Substance Registry System: p-Methoxybenzenesulfonic acid(5857-42-1)

Safety Data

• Hazardous Substances Data: 5857-42-1(Hazardous Substances Data)

Usage

General Description

p-Methoxybenzenesulfonic acid, also known as p-toluenesulfonic acid, is an organic compound with the chemical formula C7H8O3S. It is a white crystalline solid that is soluble in water and organic solvents. p-Methoxybenzenesulfonic acid is commonly used as a catalyst and acid in organic synthesis, particularly in esterification and transesterification reactions. It is also used as a strong acid in the production of pharmaceuticals, dyes, and polymers. Additionally, it is employed as an acid catalyst in the synthesis of biodiesel and as a stabilizer in the production of plastics. Due to its versatile and valuable properties, p-Methoxybenzenesulfonic acid has many industrial and laboratory applications.

Upstream product

• 67-56-1 methanol 
• 2154-66-7 4-sulfobenzenediazonium 
• 696-63-9 4-Methoxybenzenethiol 
• 3112-80-9 bis(p-anisyl)sulfone 
• 1709-60-0 4-methoxybenzenesulfinic acid 
• 100-66-3 methoxybenzene 
• 77-78-1 dimethyl sulfate 
• 108-95-2 phenol 
• 98-67-9 p-hydoroxybenzenesulfonic acid 
• 74-88-4 methyl iodide 
• 52813-73-7 Benzoin-p-methoxyphenylsulfonester 
• 52813-75-9 4-Methoxy-benzenesulfonic acid 2-(4-chloro-phenyl)-2-oxo-1-phenyl-ethyl ester 
• 52813-77-1 4-Methoxy-benzenesulfonic acid 2-(4-methoxy-phenyl)-2-oxo-1-phenyl-ethyl ester 
• 3393-77-9 bis(4-methoxyphenyl)sulfide 

Downstream Products

• 104-92-7 1-bromo-4-methoxy-benzene 
• 91284-48-9 isopropyl p-methoxybenzenesulfonate 
• 80519-85-3 4-Methoxy-benzenesulfonic acid 2-oxo-hexyl ester 
• 80520-23-6 4-Methoxy-benzenesulfonic acid 2-oxo-undecyl ester 
• 80520-24-7 4-Methoxy-benzenesulfonic acid 2-oxo-tridecyl ester 
• 80520-21-4 4-Methoxy-benzenesulfonic acid 2-oxo-heptyl ester 
• 80520-22-5 4-Methoxy-benzenesulfonic acid 2-oxo-nonyl ester 
• 84855-90-3 4-Methoxy-benzenesulfonic acid 4-cyclohexyl-3-methyl-2-oxo-butyl ester 
• 84855-93-6 4-Methoxy-benzenesulfonic acid 3-cyclohexylmethyl-2-oxo-pentyl ester 
• 53226-51-0 p-Methoxy-benzol-sulfonsaeure-benzylester 
• 696-63-9 4-Methoxybenzenethiol 
• 5023-73-4 4-methoxybenzyl-(4'-methoxyphenyl)-sulfide 
• 98830-64-9 cinnamyl(4-methoxyphenyl)sulfane 
• 25963-47-7 4-Sulfanilyl-phenol 

Relevant articles and documents

Cyclodextrin-surfactant binding constant as driven force for uncomplexed cyclodextrin in equilibrium with micellar systems

Mixed systems formed by surfactants, sodium alkylsulfonates, and β-cyclodextrin have been studied by using the solvolysis of 4-methoxybenzenesulfonil chloride (MBSC) as a chemical probe. The kinetic analysis allows us to obtain the percentage of uncomplex

Cucurbit[7]uril: Surfactant host-guest complexes in equilibrium with micellar aggregates

In order to compare the formation of host-guest complexes between β-cyclodextrin (β-CD) or cucurbit[7]uril (CB7) and cationic surfactants we studied the hydrolysis of 4-methoxybenzenesulfonyl chloride (MBSC). The selected surfactants allowed the length of

Aryl and alkyl sulfonic acid compounds as well as construction method adopting inorganic sulfur salt and application

The invention discloses aryl and alkyl sulfonic acid compounds as shown in a formula (1) and a synthesis method thereof. The method comprises the following step: aromatic iodine and an inorganic sulfur source or alkyl bromide and an inorganic sulfur source as reaction raw materials react in a solvent under the action of alkali, a catalyst or an additive to obtain a series of aryl and alkyl sulfonic acid compounds. According to the method, the aryl and alkyl sulfonic acid compounds are constructed in one step by taking an inorganic sulfur reagent as a sulfur source, so that the defect of the mode in which the aryl and alkyl sulfonic acid compounds are synthesized by taking concentrated sulfuric acid, chlorosulfonic acid or sulfur dioxide gas and the like as sulfonating reagents in the priorart is avoided. The aryl and alkyl sulfonic acid compounds developed by the invention can be used for synthesizing aryl and alkyl sulfonic acid drug analogues.

Sustainable access to sulfonic acids from halides and thiourea dioxide with air

A sustainable and mild one-step strategy is explored for the synthesis of aryl and alkyl sulfonic acids using a facile combination of halides and sulfur dioxide surrogates under air. The cheap industrial material thiourea dioxide was employed as an eco-friendly and easy-handling sulfur dioxide surrogate, while air was used as a green oxidant. Both aryl and alkyl sulfonic acids were obtained under transition metal-catalyzed or transition metal-free conditions. Mechanistic studies demonstrated that sulfinate was involved as an intermediate in this transformation. Notably, this protocol has been applied to the late-stage sulfonation of the drugs naproxen, isoxepac and ibuprofen.

Silver-Mediated Trifluoromethoxylation of (Hetero)aryldiazonium Tetrafluoroborates

Here we report a silver-mediated trifluoromethoxylation of (hetero)aryldiazonium tetrafluoroborates by converting an aromatic amino group into an OCF3 group. This method, which can be considered to be a trifluoromethoxylation variation of the classic Sandmeyer-type reaction, uses readily available aryl and heteroaromatic amines as starting materials and AgOCF3 as trifluoromethoxylating reagents. The broad substrate scope and simple, mild reaction condition made this transformation a valuable method in constructing aryl-OCF3 bonds.