58579-54-7

Basic information

• Product Name: 1-broMo-2-(broMoMethyl)-3-nitrobenzene
• Synonyms: 1-broMo-2-(broMoMethyl)-3-nitrobenzene;2-Bromo-6-nitrobenzyl bromide
• CAS NO: 58579-54-7
• Molecular Formula: C₇H₅Br₂NO₂
• Molecular Weight: 294.9281
• EINECS: 1308068-626-2
• Mol File: 58579-54-7.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-broMo-2-(broMoMethyl)-3-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-broMo-2-(broMoMethyl)-3-nitrobenzene(58579-54-7)
• EPA Substance Registry System: 1-broMo-2-(broMoMethyl)-3-nitrobenzene(58579-54-7)

Safety Data

• Hazardous Substances Data: 58579-54-7(Hazardous Substances Data)

Usage

Description

1-broMo-2-(broMoMethyl)-3-nitrobenzene is an organic compound characterized by its bromine and nitro functional groups. It is a versatile intermediate in the synthesis of various organic molecules and has potential applications in different industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
1-broMo-2-(broMoMethyl)-3-nitrobenzene is used as a synthetic intermediate for the development of new pharmaceutical compounds. Its bromine and nitro groups can be further functionalized to create a wide range of drug candidates with potential therapeutic applications.
Used in Chemical Synthesis:
1-broMo-2-(broMoMethyl)-3-nitrobenzene is used as a reagent in the synthesis of various organic compounds, including 3and 4-substituted indoles. Its unique structure allows for selective functionalization and reaction with other molecules, making it a valuable building block in organic chemistry.
Used in Material Science:
1-broMo-2-(broMoMethyl)-3-nitrobenzene is used as a component in the preparation of acid photogenerators for lithographic resist applications. Its ability to undergo specific chemical reactions makes it a useful starting material for the development of advanced materials with potential applications in microelectronics and other high-tech industries.

Upstream product

• 55289-35-5 2-bromo-6-nitrotoluene 
• 603-83-8 3-nitro-o-tolylamine 

Downstream Products

• 109513-33-9 C₁₅H₁₄BrN₃O₃ 
• 132898-42-1 2-nitro-6-bromobenzyl tosylate 
• 1033820-57-3 C₁₇H₁₆BrNO₅ 
• 109019-72-9 1-(2-Bromo-6-nitrobenzyl)pyridinium bromide 
• 861106-66-3 5-bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one 
• 861106-65-2 3-bromo-2-((methylamino)methyl)aniline 
• 1622303-33-6 N-(3-bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)-4-(1-methylcyclopropyl)benzamide 
• 1198765-14-8 N-(3-bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)-4-cyclopropyl-2-methylbenzamide 
• 1147531-08-5 N-(2-(((tert-butyldimethylsilyl)oxy)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-(dimethylamino)benzamide 
• 1622303-14-3 N-(3-bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)-4-(dimethylamino)benzamide 
• 1361941-11-8 2-bromo-6-(2-tert-butyl-6-oxo-4H-thieno[3,2-c]pyrrol-5(6H)-yl)benzyl acetate 
• 1361941-10-7 5-(3-bromo-2-(hydroxymethyl)phenyl)-2-tert-butyl-4H-thieno[3,2-c]pyrrol-6(5H)-one 
• 1361941-09-4 3-((3-Bromo-2-(hydroxymethyl)phenylamino)methyl)-5-tert-butylthiophene-2-carboxylic acid 
• 1361941-08-3 methyl 3-((3-bromo-2-((tert-butyldimethylsilyloxy)methyl)-phenylamino)methyl)-5-tert-butylthiophene-2-carboxylate 

Relevant articles and documents

Novel Bruton's tyrosine kinase inhibitor as well as preparation method and application thereof

The invention relates to a reversible novel Bruton's tyrosine kinase inhibitor which comprises a compound of a formula (I) as shown in the specification, and a stereisomer, a aquo-complex, a solvent compound, a pharmaceutically acceptable salt, an eutectic crystal or a predrug of the compound. The invention further relates to a preparation method of the compound and a method and the application ofthe novel compound in inhibiting BTK (Bruton's Tyrosine Kinase) kinase activity and mutant BTK kinase activity.

SUBSTITUTED 1H-PYRROLOPYRIDINONE DERIVATIVES AS KINASE INHIBITORS

The present invention provides novel substituted 1H-Pyrrolopyridinone derivatives of formula (1) as protein kinase inhibitors, in which R1, R2, R3, R4, R5, R6 and 'p' have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage in inhibiting kinase enzyme, more particularly BTK enzyme. The present invention also provides methods for synthesizing and administering the kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

PYRIDINONES/PYRAZINONES, METHOD OF MAKING, AND METHOD OF USE THEREOF

Pyridone and pyrazinone compounds of Formula (I) including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.