58598-96-2

Basic information

• Product Name: Pyridine, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-
• CAS NO: 58598-96-2
• Molecular Formula: C13H9N3O
• Molecular Weight: 223.234
• Mol File: 58598-96-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-(58598-96-2)
• EPA Substance Registry System: Pyridine, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-(58598-96-2)

Safety Data

• Hazardous Substances Data: 58598-96-2(Hazardous Substances Data)

Upstream product

• 100-70-9 2-Cyanopyridine 
• 873-67-6 benzonitrile oxide 
• 1448510-47-1 3-phenyl-5-(2-pyridyl)-1,2,4-oxadiazole-4-oxide 
• 1772-01-6 2-pyridylamidoxime 
• 698-16-8 benzohydroximoyl chloride 
• 100-47-0 benzonitrile 
• 1121-60-4 pyridine-2-carbaldehyde 
• 613-92-3 N-hydroxybenzenecarboximidamide 
• 100-69-6 2-vinylpyridine 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 100-52-7 benzaldehyde 
• 932-90-1 Benzaldoxime 

Relevant articles and documents

TBAI/TBHP-Catalyzed Synthesis of [1,2,4]Triazolo[4,3-a]pyridines and 3,5-Diaryl-1,2,4-oxadiazoles via Oxidative Cleavage of C=C Double Bond

Abstract: A simple and efficient protocol has been described for the synthesis of [1,2,4]triazolo[4,3-a]pyri-dines and 3,5-disubstituted-1,2,4-oxadiazoles by reacting 2-hydrazinylpyridine and benzamidoximes, respec-tively, with styrenes via TBAI/TBHP-mediated oxidative cleavage of C=C bond under ligand- and metal-free conditions.

Beyond direct Nrf2 activation; reinvestigating 1,2,4-oxadiazole scaffold as a master key unlocking the antioxidant cellular machinery for cancer therapy

Harnessing the antioxidant cellular machinery has sparked considerable interest as an efficient anticancer strategy. Activating Nrf2, the master switch of the cellular redox system, suppresses ROS, alleviates oxidative stress, and halts cancer progression

Facile room-temperature assembly of the 1,2,4-oxadiazole core from readily available amidoximes and carboxylic acids

A one-pot ambient-temperature procedure for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles from amidoximes and carboxylic acids under superbase-promoted conditions is reported.