58751-83-0

Basic information

• Product Name: 1-Propanone, 1,2-diphenyl-, (2R)-
• CAS NO: 58751-83-0
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Mol File: 58751-83-0.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1,2-diphenyl-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1,2-diphenyl-, (2R)-(58751-83-0)
• EPA Substance Registry System: 1-Propanone, 1,2-diphenyl-, (2R)-(58751-83-0)

Safety Data

• Hazardous Substances Data: 58751-83-0(Hazardous Substances Data)

Upstream product

• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 100-58-3 phenylmagnesium bromide 
• 7782-26-5 (R)-2-Phenylpropionic acid 
• 14037-02-6 2-(2-phenyl-propenyl)-pyridine 
• 1832-41-3 2-bromo-1,2-diphenyl-propan-1-one 
• 66323-99-7 trimethyl[(Z)-(1-phenyl-1-propenyl)oxy]silane 
• 144930-50-7 mesityl(phenyl)iodonium triflouromethanesulfonate 
• 22293-10-3 (1-diazoethyl)benzene 
• 100-52-7 benzaldehyde 
• 119-61-9 benzophenone 
• 778-66-5 1,1-diphenyl-1-propene 
• 38821-25-9 α-octyl deoxybenzoin 
• 52072-37-4 α-hexyl deoxybenzoin 
• 451-40-1 phenyl benzyl ketone 

Downstream Products

• 1857-74-5 2,3-diphenylbutane 
• 134-81-6 benzil 
• 18220-90-1 4-ethylbenzophenone 
• 89103-72-0 (1S,2S)-1,2-diphenylpropan-1-ol 
• 7693-84-7 (1R,2R)-1,2-diphenyl-propan-1-ol 
• 28795-94-0 1,2-diphenyl-1-propanol 
• 951-85-9 (S)-methyldesoxybenzoin 

Relevant articles and documents

Decoding stereocontrol during the photooxygenation of oxazolidinone- functionalized enecarbamates

Figure presented Systematically designed oxazolidinone-derived enecarbamates reveal that solvent and temperature effects on the stereoselectivity during photooxygenation are likely due to the conformational flexibility of the chiral phenethyl side chain (entropy factors); the extent of enantiomeric excess in the photoproduct is dictated by the alkene geometry.

Catalytic Reductive Cross Coupling and Enantioselective Protonation of Olefins to Construct Remote Stereocenters for Azaarenes

A novel enantioselective protonation protocol that is triggered by reductive cross coupling of olefins is reported. When under cooperative photoredox and chiral hydrogen-bonding catalytic conditions and using a terminal reductant, various α-branched vinyl

Combined Photoredox and Carbene Catalysis for the Synthesis of Ketones from Carboxylic Acids

As a key element in the construction of complex organic scaffolds, the formation of C?C bonds remains a challenge in the field of synthetic organic chemistry. Recent advancements in single-electron chemistry have enabled new methods for the formation of various C?C bonds. Disclosed herein is the development of a novel single-electron reduction of acyl azoliums for the formation of ketones from carboxylic acids. Facile construction of the acyl azolium in situ followed by a radical–radical coupling was made possible merging N-heterocyclic carbene (NHC) and photoredox catalysis. The utility of this protocol in synthesis was showcased in the late-stage functionalization of a variety of pharmaceutical compounds. Preliminary investigations using chiral NHCs demonstrate that enantioselectivity can be achieved, showcasing the advantages of this protocol over alternative methodologies.