59151-15-4

Basic information

• Product Name: [1,1'-biphenyl]-4-carbaldehyde-α-d₁
• Synonyms: [1,1'-biphenyl]-4-carbaldehyde-α-d₁
• CAS NO: 59151-15-4
• Molecular Weight: 183.214
• Mol File: 59151-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1,1'-biphenyl]-4-carbaldehyde-α-d₁(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-biphenyl]-4-carbaldehyde-α-d₁(59151-15-4)
• EPA Substance Registry System: [1,1'-biphenyl]-4-carbaldehyde-α-d₁(59151-15-4)

Safety Data

• Hazardous Substances Data: 59151-15-4(Hazardous Substances Data)

Upstream product

• 917-71-5 deuterated formic acid 
• 1591-31-7 4-iodo-biphenyl 

Relevant articles and documents

A Convenient Palladium-Catalyzed Reductive Carbonylation of Aryl Iodides with Dual Role of Formic Acid

Palladium-catalyzed reductive carbonylation of aryl halides represents a straightforward pathway for the synthesis of aromatic aldehydes. The known reductive carbonylation procedures either require CO gas or complexed compounds as CO sources. In this communication, we developed a palladium-catalyzed reductive carbonylation of aryl iodides with formic acid as the formyl source. As a convenient, practical, and environmental friendly methodology, no additional silane or H2 was required. A variety of aromatic aldehydes were isolated in moderate to excellent yields under mild reaction conditions. Notably, this is the first procedure on using formic acid as the formyl source. Say no to CO gas! A convenient, practical, and environmental friendly palladium-catalyzed reductive carbonylation of aryl iodides with formic acid as the formyl source has been developed (see scheme). No additional silane or H2 was required here. A variety of aromatic aldehydes were isolated in moderate to excellent yields under mild reaction conditions.