5927-57-1

Basic information

• Product Name: Chloroacetic acid, hexyl ester
• Synonyms: Chloroacetic acid, hexyl ester;hexyl 2-chloroacetate
• CAS NO: 5927-57-1
• Molecular Formula: C₈H₁₅ClO₂
• Molecular Weight: 178.66
• Mol File: 5927-57-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 213.2°C at 760 mmHg
• Flash Point: 102.3°C
• Appearance: /
• Density: 1.018g/cm³
• Vapor Pressure: 0.166mmHg at 25°C
• Refractive Index: 1.434
• CAS DataBase Reference: Chloroacetic acid, hexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Chloroacetic acid, hexyl ester(5927-57-1)
• EPA Substance Registry System: Chloroacetic acid, hexyl ester(5927-57-1)

Safety Data

• Hazardous Substances Data: 5927-57-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H15ClO2/c1-2-3-4-5-6-11-8(10)7-9/h2-7H2,1H3

Upstream product

• 79-04-9 chloroacetyl chloride 
• 111-27-3 hexan-1-ol 
• 79-11-8 chloroacetic acid 

Downstream Products

• 36556-16-8 (4-oxo-2-phenyl-4H-chromen-7-yloxy)-acetic acid hexyl ester 
• 102960-19-0 Hexyloxycarbonylmethyl-triphenyl-phosphonium-chlorid 

Relevant articles and documents

Cyanine type modified compound Intermediate and preparation method and application thereof

The invention provides a cyanine type modified compound with the structure of the formula (I), and also provides a preparation method of the cyanine type modified compound. The Vinamidinium-salt new synthetic route is developed, the process parameters are optimized, the yield of the intermediate is improved, the product quality is also good, and the effect of increasing the yield of the next step is crucial. In addition, since the cyanine-based modified compound contains more double bonds and strong electron-withdrawing groups, it can be used as an ultraviolet - blue light absorbent.

Soft antimicrobial agents: Synthesis and activity of labile environmentally friendly long chain quaternary ammonium compounds

A series of soft quaternary ammonium antimicrobial agents, which are analogues to currently used quaternary ammonium preservatives such as cetyl pyridinium chloride and benzalkonium chloride, were synthesized. These soft analogues consist of long alkyl chain connected to a polar headgroup via chemically labile spacer group. They are characterized by facile nonenzymatic and enzymatic degradation to form their original nontoxic building blocks. However, their chemical stability has to be adequate in order for them to have antimicrobial effects. Stability studies and antibacterial and antiviral activity measurements revealed relationship between activity, lipophilicity, and stability. Their minimum inhibitory concentration (MIC) was as low as 1 μg/mL, and their viral reduction was in some cases greater than 6.7 log. The structure-activity studies demonstrate that the bioactive compounds (i.e., MIC for Gram-positive bacteria of 10μg/mL) have an alkyl chain length between 12 and 18 carbon atoms, with a polar headgroup preferably of a small quaternary ammonium group, and their acquired inactivation half-life must be greater than 3 h at 60 °C.