597-12-6 Usage
Description
D-(+)-Melezitose, a trisaccharide produced by insects such as aphids, is a naturally occurring carbohydrate with potential therapeutic applications. It is known for its unique structure and properties, which make it a promising candidate for various uses in the medical and pharmaceutical industries.
Uses
Used in Pharmaceutical Industry:
D-(+)-Melezitose is used as a therapeutic agent for the treatment of cancer, autoimmune diseases, and infectious diseases. Its application in this industry is due to its potential to modulate immune responses and exhibit anti-cancer properties, making it a valuable compound for the development of novel treatments.
Used in Cancer Treatment:
D-(+)-Melezitose is used as an anticancer agent, targeting various types of cancer by modulating the immune system and interfering with cancer cell growth and proliferation. Its application in cancer treatment is based on its ability to enhance the body's natural defense mechanisms against cancer cells and potentially improve the effectiveness of conventional cancer therapies.
Used in Autoimmune Disease Treatment:
D-(+)-Melezitose is used as an immunomodulatory agent for the treatment of autoimmune diseases. Its application in this area is due to its potential to regulate the immune system, which can help in managing the symptoms and progression of autoimmune conditions.
Used in Infectious Disease Treatment:
D-(+)-Melezitose is used as an immunostimulant for the treatment of infectious diseases. Its application in this field is based on its ability to boost the immune system's response to pathogens, potentially aiding in the prevention and treatment of various infections.
Purification Methods
D(+)-Melezitose crystallises from aqueous EtOH as the monohydrate and water as the dihydrate, and is then dried at 110o (anhydrous). It is also purified by dissolving in an equal volume of H2O, filtering into a crystallising dish and allowing to stand (loosely covered) for several weeks undisturbed at 20o. The crystals of clear prisms are wiped carefully and dried in air. They effloresce at once losing 3.35% of their weight, and after 3days in air the loss is for 1H2O from the dihydrate. Drying at 110o for 6hours in vacuo yields the anhydrous form which after 2days in air it absorbs H2O to give the monohydrate. The monohydrate is also obtained by dissolving it in an equal weight of H2O at 60o and adding 4 volumes of 95% EtOH and drying in air overnight. [Richtmeyer & Hudson J Org Chem 11 610 1946, Beilstein 17 III/IV 3815, 17/8 V 414.]
Check Digit Verification of cas no
The CAS Registry Mumber 597-12-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 597-12:
(5*5)+(4*9)+(3*7)+(2*1)+(1*2)=86
86 % 10 = 6
So 597-12-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H32O16/c19-1-5-8(23)11(26)13(28)16(30-5)32-15-10(25)7(3-21)33-18(15,4-22)34-17-14(29)12(27)9(24)6(2-20)31-17/h5-17,19-29H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15+,16-,17-,18+/m1/s1
597-12-6Relevant articles and documents
COMBINED USE OF DIPEPTIDYL PEPTIDASE IV INHIBITOR COMPOUND AND SWEETENER
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, (2010/01/29)
The present invention provides a novel therapeutic or preventive method, a pharmaceutical composition and use thereof, that exhibit superior anti-obesity effects (body weight-reducing (losing) effects and/or body fat mass-reducing effects). Specifically, the present invention provides a pharmaceutical composition comprising the combination of a dipeptidyl peptidase 4 inhibitor and a sweetener having a GLP-1 secretion-stimulating action, as well as use thereof for the manufacture of a medicament. The present invention also provides a method for treating or preventing obesity, comprising administering an effective amount of (a) a dipeptidyl peptidase 4 inhibitor and (b) a sweetener having a GLP-1 secretion-stimulating action to a patient suffering from symptoms of obesity.
